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Chapter
Hepatic Coma
Hepatic encephalopathy (HE) arises as a complication in fulminant hepatic failure (FHF) as well as in chronic liver failure. Initially it is characterized by minor mental and personality changes and discrete c...
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Article
Pathophysiology of Hepatic Encephalopathy: Results of the Hannover Consensus Conference
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Article
The Basal Ganglia and Portal-Systemic Encephalopathy
Despite decades of research, the pathogenesis of portal-systemic encephalopathy (PSE) remains puzzling. Current hypotheses on the pathophysiology of PSE usually deal with metabolic toxins like ammonia or distu...
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Article
Altered Striatal Dopamine D2 Receptor Density and Dopamine Transport in a Patient with Hepatic Encephalopathy
A patient suffering from liver cirrhosis presented with a bradykinetic-rigid syndrome suspected as Parkinson's disease. A detailed work-up of the case revealed hepatic encephalopathy as the cause of the neurol...
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Article
Altered striatal dopamine D2 receptor density and dopamine transport in a patient with hepatic encephalopathy
A patient suffering from liver cirrhosis presented with a bradykinetic-rigid syndrome suspected as Parkinson's disease. A detailed work-up of the case revealed hepatic encephalopathy as the cause of the neurol...
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Article
Attention Deficits in Minimal Hepatic Encephalopathy
Minimal hepatic encephalopathy (HE) is characterized by a decrease of psychomotor speed, and deficits in visual perception, visuo-spatial orientation, and visuo-constructive abilities. Attention deficits have ...
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Article
Correlations Between Cerebral Glucose Metabolism and Neuropsychological Test Performance in Nonalcoholic Cirrhotics
Many cirrhotics have abnormal neuropsychological test scores. To define the anatomical–physiological basis for encephalopathy in nonalcoholic cirrhotics, we performed resting-state fluorodeoxyglucose positron ...
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Preface
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Article
Functional Imaging of the Brain in Patients with Liver Cirrhosis
Brain imaging techniques have provided substantial insight into the pathophysiology of hepatic encephalopathy (HE). Magnetic resonance imaging gave hint to the fact that there is an increased deposition of man...
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Article
Attention, Memory, and Cognitive Function in Hepatic Encephalopathy
Deficits in attention and arousal play a major role in the clinical presentation of hepatic encephalopathy. Attention deficits arealso the main components of minimal hepatic encephalopathy. The present paper s...
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Article
Correlative assessment of cerebral blood flow obtained with perfusion CT and positron emission tomography in symptomatic stenotic carotid disease
Twelve patients with ICA stenosis underwent dynamic perfusion computed tomography (CT) and positron emission tomography (PET) studies at rest and after acetazolamide challenge. Cerebral blood flow (CBF) maps o...
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Article
Introduction
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Article
The treatment of hepatic encephalopathy
Current recommendations for the treatment of hepatic encephalopathy are based, to a large extent, on open or uncontrolled trials, undertaken in very small numbers of patients. In consequence, there is ongoing ...
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Article
Intra-arterial thrombolysis using rt-PA in patients with acute stroke due to vessel occlusion of anterior and/or posterior cerebral circulation
The aim of our study was to evaluate the safety and efficacy of intra-arterial (IA) thrombolysis using recombinant tissue plasminogen activator (rt-PA) in patients with acute stroke due to occlusion in the ant...
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Chapter
Hepatic Encephalopathy
Hepatic encephalopathy (HE) is a neuropsychiatric syndrome associated with severe, acute and chronic liver failure. According to the recommendations of a working party (Ferenci et al., 2002) held at the 4th World...
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Article
Hepatitis C virus infection and the brain
There is growing evidence that hepatitis C virus (HCV)-infection may affect the brain. About half of the HCV-infected patients complain of chronic fatigue irrespective of their stage of liver disease or virus ...
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Article
Introduction
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Article
Hepatic encephalopathy after treatment with temozolomide
Temozolomide in combination with radiation has been in use for more than 5 years for the therapy of glioblastoma. Known adverse effects concerning the gastrointestinal system are elevation of liver enzymes. We...
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Article
Open AccessCirculating Damage Marker Profiles Support a Neuroprotective Effect of Erythropoietin in Ischemic Stroke Patients
The German Multicenter EPO Stroke Trial, which investigated safety and efficacy of erythropoietin (EPO) treatment in ischemic stroke, was formally declared a negative study. Exploratory subgroup analysis, howe...
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Article
Open AccessAssociation of dimethylarginines and mediators of inflammation after acute ischemic stroke
Elevated levels of asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are accompanied by endothelial dysfunction and predict adverse outcome after ischemic stroke. Via induction of oxidat...