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  1. No Access

    Chapter

    Hepatic Coma

    Hepatic encephalopathy (HE) arises as a complication in fulminant hepatic failure (FHF) as well as in chronic liver failure. Initially it is characterized by minor mental and personality changes and discrete c...

    Karin Weissenborn, Luis Marsano, Anna Mae Diehl, Klaus Kunze in Neurocritical Care (1994)

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    Article

    Pathophysiology of Hepatic Encephalopathy: Results of the Hannover Consensus Conference

    Karin Weissenborn in Metabolic Brain Disease (1998)

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    Article

    The Basal Ganglia and Portal-Systemic Encephalopathy

    Despite decades of research, the pathogenesis of portal-systemic encephalopathy (PSE) remains puzzling. Current hypotheses on the pathophysiology of PSE usually deal with metabolic toxins like ammonia or distu...

    Karin Weissenborn, Hans Kolbe in Metabolic Brain Disease (1998)

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    Article

    Altered Striatal Dopamine D2 Receptor Density and Dopamine Transport in a Patient with Hepatic Encephalopathy

    A patient suffering from liver cirrhosis presented with a bradykinetic-rigid syndrome suspected as Parkinson's disease. A detailed work-up of the case revealed hepatic encephalopathy as the cause of the neurol...

    Karin Weissenborn, Georg Berding, Herbert Köstler in Metabolic Brain Disease (2000)

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    Article

    Altered striatal dopamine D2 receptor density and dopamine transport in a patient with hepatic encephalopathy

    A patient suffering from liver cirrhosis presented with a bradykinetic-rigid syndrome suspected as Parkinson's disease. A detailed work-up of the case revealed hepatic encephalopathy as the cause of the neurol...

    Karin Weissenborn, Georg Berding, Herbert Köstler in Metabolic Brain Disease (2000)

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    Article

    Attention Deficits in Minimal Hepatic Encephalopathy

    Minimal hepatic encephalopathy (HE) is characterized by a decrease of psychomotor speed, and deficits in visual perception, visuo-spatial orientation, and visuo-constructive abilities. Attention deficits have ...

    Karin Weissenborn, Susanne Heidenreich, Jochen Ennen in Metabolic Brain Disease (2001)

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    Article

    Correlations Between Cerebral Glucose Metabolism and Neuropsychological Test Performance in Nonalcoholic Cirrhotics

    Many cirrhotics have abnormal neuropsychological test scores. To define the anatomical–physiological basis for encephalopathy in nonalcoholic cirrhotics, we performed resting-state fluorodeoxyglucose positron ...

    Alan H. Lockwood, Karin Weissenborn, Martin Bokemeyer, U. Tietge in Metabolic Brain Disease (2002)

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    Article

    Preface

    Michael P. Manns, Karin Weissenborn in Metabolic Brain Disease (2004)

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    Article

    Functional Imaging of the Brain in Patients with Liver Cirrhosis

    Brain imaging techniques have provided substantial insight into the pathophysiology of hepatic encephalopathy (HE). Magnetic resonance imaging gave hint to the fact that there is an increased deposition of man...

    Karin Weissenborn, Martin Bokemeyer, Björn Ahl in Metabolic Brain Disease (2004)

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    Article

    Attention, Memory, and Cognitive Function in Hepatic Encephalopathy

    Deficits in attention and arousal play a major role in the clinical presentation of hepatic encephalopathy. Attention deficits arealso the main components of minimal hepatic encephalopathy. The present paper s...

    Karin Weissenborn, Kathrin Giewekemeyer, Susanne Heidenreich in Metabolic Brain Disease (2005)

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    Article

    Correlative assessment of cerebral blood flow obtained with perfusion CT and positron emission tomography in symptomatic stenotic carotid disease

    Twelve patients with ICA stenosis underwent dynamic perfusion computed tomography (CT) and positron emission tomography (PET) studies at rest and after acetazolamide challenge. Cerebral blood flow (CBF) maps o...

    Sotirios Bisdas, Ole Nemitz, Georg Berding, Karin Weissenborn in European Radiology (2006)

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    Article

    Introduction

    Karin Weissenborn, Michael P. Manns in Metabolic Brain Disease (2007)

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    Article

    The treatment of hepatic encephalopathy

    Current recommendations for the treatment of hepatic encephalopathy are based, to a large extent, on open or uncontrolled trials, undertaken in very small numbers of patients. In consequence, there is ongoing ...

    Marsha Y. Morgan, A. Blei, K. Grüngreiff, R. Jalan, G. Kircheis in Metabolic Brain Disease (2007)

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    Article

    Intra-arterial thrombolysis using rt-PA in patients with acute stroke due to vessel occlusion of anterior and/or posterior cerebral circulation

    The aim of our study was to evaluate the safety and efficacy of intra-arterial (IA) thrombolysis using recombinant tissue plasminogen activator (rt-PA) in patients with acute stroke due to occlusion in the ant...

    Argyro Tountopoulou, Bjoern Ahl, Karin Weissenborn, Hartmut Becker in Neuroradiology (2008)

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    Chapter

    Hepatic Encephalopathy

    Hepatic encephalopathy (HE) is a neuropsychiatric syndrome associated with severe, acute and chronic liver failure. According to the recommendations of a working party (Ferenci et al., 2002) held at the 4th World...

    Karin Weissenborn in Metabolic Encephalopathy (2009)

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    Article

    Hepatitis C virus infection and the brain

    There is growing evidence that hepatitis C virus (HCV)-infection may affect the brain. About half of the HCV-infected patients complain of chronic fatigue irrespective of their stage of liver disease or virus ...

    Karin Weissenborn, Anita B. Tryc, Meike Heeren, Hans Worthmann in Metabolic Brain Disease (2009)

  17. Article

    Introduction

    Michael P. Manns, Karin Weissenborn in Metabolic Brain Disease (2010)

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    Article

    Hepatic encephalopathy after treatment with temozolomide

    Temozolomide in combination with radiation has been in use for more than 5 years for the therapy of glioblastoma. Known adverse effects concerning the gastrointestinal system are elevation of liver enzymes. We...

    Annemarie Goldbecker, Anita Blanka Tryc, Peter Raab in Journal of Neuro-Oncology (2011)

  19. Article

    Open Access

    Circulating Damage Marker Profiles Support a Neuroprotective Effect of Erythropoietin in Ischemic Stroke Patients

    The German Multicenter EPO Stroke Trial, which investigated safety and efficacy of erythropoietin (EPO) treatment in ischemic stroke, was formally declared a negative study. Exploratory subgroup analysis, howe...

    Hannelore Ehrenreich, Anne Kästner, Karin Weissenborn in Molecular Medicine (2011)

  20. Article

    Open Access

    Association of dimethylarginines and mediators of inflammation after acute ischemic stroke

    Elevated levels of asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are accompanied by endothelial dysfunction and predict adverse outcome after ischemic stroke. Via induction of oxidat...

    Shufen Chen, Jens Martens-Lobenhoffer, Karin Weissenborn in Journal of Neuroinflammation (2012)

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