30 Result(s)

Article

Investigation of Hardness, Microstructure, and Process Temperature in the Internal Gear Flow-Forming Process

The advantages of the flow-forming process, such as excellent mechanical properties, simple tools, and the need for low forming force, have led to the increasing use of this process in various industries, espe...

M. Khodadadi, K. Khalili, A. Ashrafi, F. Kolahan in Experimental Techniques (2023)

Article

Development and application of a new index for analyzing temperature concentration for Iran’s climate

Spatiotemporal variation of temperature and precipitation helps in classification of type of climate of each region and affects the availability of access of drinking water to the inhabitants in the region. A ...

M. Nazeri Tahroudi, K. Khalili, F. Ahmadi… in International Journal of Environmental Sci… (2019)

Article

Studying the effect of material initial conditions on drying induced stresses

Cracking as a result of non-uniform deformation during drying is one of defects that may occur during drying and has to be dealt with by proper drying treatment. In the current study the effect of initial cond...

M. Heydari, K. Khalili, S. Y. Ahmadi-Brooghani in Heat and Mass Transfer (2018)

Article

A method based on spindle motor current harmonic distortion measurements for tool wear monitoring

This paper deals with an indirect measurement of tool wear from spindle motor current. The main focus of this paper is on harmonic analysis of motor current. In this research, the nonlinear harmonic distortion...

A. Akbari, M. Danesh, K. Khalili in Journal of the Brazilian Society of Mechan… (2017)

Article

Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study

A CRISPR/Cas9 gene editing strategy has been remarkable in excising segments of integrated HIV-1 DNA sequences from the genome of latently infected human cell lines and by introducing InDel mutations, suppress...

R Kaminski, R Bella, C Yin, J Otte, P Ferrante, H E Gendelman, H Li… in Gene Therapy (2016)

Article

Investigation on the Effect of Young’s Modulus Variation on Drying-Induced Stresses

The aim of this study is to evaluate the effect of Young’s modulus changes in different moistures on convective drying-induced stresses. A number of different geometries with axial symmetry were studied for bo...

M. Heydari, K. Khalili in Transport in Porous Media (2016)

Article

Multi-objective Optimization of Welding Parameters in Submerged Arc Welding of API X65 Steel Plates

Submerged arc welding (SAW) is one of the main welding processes with high deposition rate and high welding quality. This welding method is extensively used in welding large-diameter gas transmission pipelines...

M. A. Moradpour, S. H. Hashemi, K. Khalili in Journal of Iron and Steel Research Interna… (2015)

Article

Loading path optimization of a hydroformed part using multilevel response surface method

In tube hydroforming, the loading path that is the relationship between axial feeding and internal fluid pressure is of important significance. Researchers have employed various optimization approaches to find...

S. Y. Ahmadi Brooghani, K. Khalili… in The International Journal of Advanced Manu… (2014)

Article

FEM analysis of edge preparation for chamfered tools

The chamfer enhances the performance of the tool by strengthening the edge and reducing the possibility of tool wear and breakage. The strength of the chamfered tool can be investigated by analysis of process ...

K. Khalili, M. Safaei in International Journal of Material Forming (2009)

Article

Activation of BAG3 by Egr-1 in response to FGF-2 in neuroblastoma cells

The co-chaperone protein, BAG3, which belongs to the BAG protein family, has an established antiapoptotic function in different tumor cell lines. Here we demonstrated that treatment of the human neuroblastoma ...

A Gentilella, G Passiatore, S Deshmane, M C Turco, K Khalili in Oncogene (2008)

Article

Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin

The human immunodeficiency virus type 1 (HIV-1) viral protein R (vpr) gene is an evolutionarily conserved gene among the primate lentiviruses. Several functions are attributed to Vpr including the ability to caus...

K Siddiqui, L Del Valle, N Morellet, J Cui, M Ghafouri, R Mukerjee, K Urbanska… in Oncogene (2008)

Article

A novel role of Rac1 GTPase in JCV T-antigen-mediated β-catenin stabilization

Wnt signaling follows canonical and non-canonical pathways to regulate a variety of processes during cellular homeostasis and development. The large T-antigen (T-Ag) of the human neurotropic JC virus, has been...

R Bhattacharyya, E K Noch, K Khalili in Oncogene (2007)

Article

Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3β constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines

We have previously reported that insulin-like growth factor-I (IGF-I) supports growth and survival of mouse and human medulloblastoma cell lines, and that IGF-I receptor (IGF-IR) is constitutively phosphorylat...

K Urbanska, J Trojanek, L Del Valle, M B Eldeen, F Hofmann, C Garcia-Echeverria… in Oncogene (2007)

Article

Interaction of retinoblastoma protein family members with large T-antigen of primate polyomaviruses

The retinoblastoma gene product pRb and other members of the Rb family of pocket proteins have a central role in the regulation of cell cycle progression. Soon after its discovery, pRb was found to interact wi...

M K White, K Khalili in Oncogene (2006)

Article

Role of the interaction between large T antigen and Rb family members in the oncogenicity of JC virus

Human polyomaviruses (JC virus, BK virus and simian virus 40) are causative agents of some human diseases and, interestingly, are involved in processes of cell transformation and oncogenesis. These viruses nee...

V Caracciolo, K Reiss, K Khalili, G De Falco, A Giordano in Oncogene (2006)

Article

p27^SJ, a novel protein in St John's Wort, that suppresses expression of HIV-1 genome

Transcription of the HIV-1 genome is controlled by the cooperation of viral regulatory proteins and several host factors which bind to specific DNA sequences within the viral promoter spanning the long termina...

N Darbinian-Sarkissian, A Darbinyan, J Otte, S Radhakrishnan, B E Sawaya… in Gene Therapy (2006)

Article

p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes

HIV-1 Tat is a potent transcriptional activator of the viral promoter with the ability to modulate a number of cellular regulatory circuits including apoptosis. Tat exerts its effects through interaction with ...

M. Saunders, M. B. Eldeen, L. Del Valle, K. Reiss, F. Peruzzi, G. Mameli… in Apoptosis (2005)

Article

Role of perivascular macrophages trafficking in HIV associated dementia complex

J. Rappaport, T. Fischer-Smith, S. Croul, A. Adeniyi… in Journal of NeuroVirology (2004)