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Article
Integrating multidisciplinary instruments for assessing coastal vulnerability to erosion and sea level rise: lessons and challenges from the Adriatic Sea, Italy
The evolution of coastal and transitional environments depends upon the interplay of human activities and natural drivers, two factors that are strongly connected and many times conflicting. The urge for effic...
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Article
Open AccessA review of the pattern of AIDS defining, HIV associated neoplasms and premalignant lesions diagnosed from 2000–2011 at Kenyatta National Hospital, Kenya
Sub-Sahara Africa hosts up to 71 % of all HIV infected people in the world. With this high incidence of Human immunodeficiency virus ( HIV) comes the burden of co-morbidities such as malignant and premalignant...
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Article
Open AccessEpstein-Barr nuclear antigen 1 induces expression of the cellular microRNA hsa-miR-127 and impairing B-cell differentiation in EBV-infected memory B cells. New insights into the pathogenesis of Burkitt lymphoma
Epstein-Barr Virus (EBV) is a γ-herpesvirus that infects >90% of the human population. Although EBV persists in its latent form in healthy carriers, the virus is also associated with several human cancers. EBV...
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Article
The different epidemiologic subtypes of Burkitt lymphoma share a homogenous micro RNA profile distinct from diffuse large B-cell lymphoma
Sporadic Burkitt lymphoma (sBL) can be delineated from diffuse large B-cell lymphoma (DLBCL) by a very homogeneous mRNA expression signature. However, it remained unclear whether all three BL variants—sBL, end...
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Article
Open AccessHIV-1 Tat mimetic of VEGF correlates with increased microvessels density in AIDS-related diffuse large B-cell and Burkitt lymphomas
Angiogenic switch marks the beginning of tumor’s strategy to acquire independent blood supply. In some subtypes of non-Hodgkin’s lymphomas, higher local vascular endothelial growth factor (VEGF) expression cor...
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Article
Comparative analysis of macrofaunal species richness and composition in Posidonia oceanica, Cymodocea nodosa and leaf litter beds
We investigated macrofaunal species richness and composition in Posidonia oceanica, Cymodocea nodosa and Leaf litter beds within a coastal area of the Gulf of Oristano in proximity of the Cabras lagoon (western S...
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Article
Retinoblastoma gene family expression in lymphoid tissues
It appears more and more clear that retinoblastoma (RB) family of proteins represents key molecules in tumour suppression. This family consists of pRb/p105, p107 and pRb2/p130, which participate in a gene regu...
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Article
pRb: master of differentiation. Coupling irreversible cell cycle withdrawal with induction of muscle-specific transcription
The protein product of the retinoblastoma (RB) gene is necessary for the completion of the muscle differentiation program and for myogenic basic helix–loop–helix-dependent transcription. In fact, in addition t...
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Article
pRb2/p130: a new candidate for retinoblastoma tumor formation
Retinoblastoma is the most common primary intraocular tumor in childhood. Mutations in both the alleles of the RB1 gene represent the causative agent for the tumor to occur. It is becoming evident that, althou...
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Article
Role of the interaction between large T antigen and Rb family members in the oncogenicity of JC virus
Human polyomaviruses (JC virus, BK virus and simian virus 40) are causative agents of some human diseases and, interestingly, are involved in processes of cell transformation and oncogenesis. These viruses nee...
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Article
Pathologic aspects of AIDS malignancies
Since the emergence of the HIV pandemic, a close association between HIV infection and the development of a selected group of cancers has been acknowledged. The introduction of highly active antiretroviral the...
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Chapter
Concentrations of Trace Metals (Cd, Cu, Fe, Pb) in Posidonia oceanica Seagrass of Liscia Bay, Sardinia (Italy)
Heavy metal concentrations were measured in Posidonia oceanica seagrass from a Mediterranean site (Liscia bay, N Sardinia, Italy) in order to assess the degree of metal pollution in the area. Metals Cd, Cu, Fe an...
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Article
Relationship between sediment distribution and Posidonia oceanica seagrass
Relationships between sedimentary features and the distribution and structure of Posidonia oceanica meadows were investigated in the Gulf of Oristano (Sardinia) in a study site stretching from the mouth of the T...
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Chapter
Grain Size Analysis of Aerosol and Rain Particles: A Methodological Comparison
Grain size analysis of aerosol particles collected by air filtration is difficult because of the low concentration and therefore the representativeness of sub-sampling. We have analysed a set of aerosol sample...
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Chapter
The regulation of pesticides in Argentina
The first action pertaining specifically to plant protection regulation in the Republic of Argentina dates back to 4 May 1888 when, due to the occurrence of grape phylloxera in some vineyards in the province o...
