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  1. No Access

    Article

    Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia

    New treatments for adults with acute lymphoblastic T-cell leukemia (T-ALL) are urgently needed, as the current rate of overall remission in these patients is only about 40 percent. We recently showed the poten...

    K Morrow, C P Hernandez, P Raber, L Del Valle, A M Wilk, S Majumdar… in Leukemia (2013)

  2. Article

    IGF-IR-dependent expression of Survivin is required for T-antigen-mediated protection from apoptosis and proliferation of neural progenitors

    The insulin-like growth factor-1 receptor (IGF-IR) and the human polyomavirus JCV protein, T-antigen cooperate in the transformation of neuronal precursors in the cerebellum, which may be a contributing factor...

    E Gualco, K Urbanska, G Perez-Liz, T Sweet, F Peruzzi… in Cell Death & Differentiation (2010)

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  3. No Access

    Article

    Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin

    The human immunodeficiency virus type 1 (HIV-1) viral protein R (vpr) gene is an evolutionarily conserved gene among the primate lentiviruses. Several functions are attributed to Vpr including the ability to caus...

    K Siddiqui, L Del Valle, N Morellet, J Cui, M Ghafouri, R Mukerjee, K Urbanska… in Oncogene (2008)

  4. Article

    ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death

    The apoptosis-inducing Fas ligand (FasL) is a type II transmembrane protein that is involved in the downregulation of immune reactions by activation-induced cell death (AICD) as well as in T cell-mediated cyto...

    M Schulte, K Reiss, M Lettau, T Maretzky, A Ludwig… in Cell Death & Differentiation (2007)

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  5. No Access

    Article

    Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3β constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines

    We have previously reported that insulin-like growth factor-I (IGF-I) supports growth and survival of mouse and human medulloblastoma cell lines, and that IGF-I receptor (IGF-IR) is constitutively phosphorylat...

    K Urbanska, J Trojanek, L Del Valle, M B Eldeen, F Hofmann, C Garcia-Echeverria… in Oncogene (2007)

  6. No Access

    Article

    Tracking TrkA’s Trafficking: NGF Receptor Trafficking Controls NGF Receptor Signaling

    Growth factors such as the neurotrophins promote neuronal survival and shape neuronal morphology. Neurotrophin receptors are located on the surface of axons and dendrites and must convey their signal retrograd...

    T. Moises, A. Dreier, S. Flohr, M. Esser, E. Brauers, K. Reiss… in Molecular Neurobiology (2007)

  7. No Access

    Article

    Role of the interaction between large T antigen and Rb family members in the oncogenicity of JC virus

    Human polyomaviruses (JC virus, BK virus and simian virus 40) are causative agents of some human diseases and, interestingly, are involved in processes of cell transformation and oncogenesis. These viruses nee...

    V Caracciolo, K Reiss, K Khalili, G De Falco, A Giordano in Oncogene (2006)

  8. No Access

    Article

    p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes

    HIV-1 Tat is a potent transcriptional activator of the viral promoter with the ability to modulate a number of cellular regulatory circuits including apoptosis. Tat exerts its effects through interaction with ...

    M. Saunders, M. B. Eldeen, L. Del Valle, K. Reiss, F. Peruzzi, G. Mameli… in Apoptosis (2005)

  9. No Access

    Article

    Efficient in vitro and in vivo gene regulation of a retrovirally delivered pro-apoptotic factor under the control of the Drosophila HSP70 promoter

    We have developed a self-inactivating retroviral vector system with an internal, inducible Drosophila HSP70 promoter. This vector system delivers the desired transgene into cells rapidly and efficiently. It ge...

    G Romano, K Reiss, X Tu, F Peruzzi, B Belletti, J Y Wang, T Zanocco-Marani… in Gene Therapy (2001)

  10. No Access

    Chapter

    Algorithms Supporting Driver/Receiver Design for Multi-Conductor Interconnects

    Design of packaging for high speed circuits requires modeling of transmission properties of interconnecting lines. In particular the evaluation of characteristic admittance matrix of interconnections is a basi...

    O. A. Palusinski, K. Reiss, F. Szidarovszky in Signal Propagation on Interconnects (1998)

  11. No Access

    Article

    Characterization of porous alkali-metal thermoelectric converter electrodes operating at 800 °C

    R. Knödler, K. Reiss, B. Westhoven in Journal of Materials Science Letters (1992)