8 Result(s)

Article

The best linear unbiased prediction (BLUP) method as a tool to estimate the lifetime risk of pancreatic ductal adenocarcinoma in high-risk individuals with no known pathogenic germline variants

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death in the Western world. The number of diagnosed cases and the mortality rate are almost equal as the majority of patien...

Cristina-Marianini-Rios, María E. Castillo Sanchez… in Familial Cancer (2024)

Article

The Spanish Familial Pancreatic Cancer Registry (PANGENFAM): a decade follow-up of individuals at high-risk for pancreatic cancer

The Spanish Familial Pancreatic Cancer Registry (PANGENFAM) was established in 2009 and aims to characterize the genotype and phenotype of familial pancreatic cancer (FPC). Furthermore, an early detection scre...

Julie Earl, Raquel Fuentes, María E. Castillo Sanchez… in Familial Cancer (2024)

Article

ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity

Pancreatic cancer stem cells (PaCSCs) drive pancreatic cancer tumorigenesis, chemoresistance and metastasis. While eliminating this subpopulation of cells would theoretically result in tumor eradication, PaCSC...

Sonia Alcalá, Patricia Sancho, Paola Martinelli, Diego Navarro… in Nature Communications (2020)

Article

Differential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer

Exosome production from cancer-associated fibroblasts seems to be an important driver of tumor progression. We report the first in-depth biotype characterization of ncRNAs, analyzed by Next Generation Sequenci...

Mercedes Herrera, Carlos Llorens, Marta Rodríguez, Alberto Herrera… in Molecular Cancer (2018)

Article

Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies

Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau… in BMC Genomics (2016)

Article

Erratum to: The UBC-40 Urothelial Bladder Cancer Cell Line Index: a genomic resource for functional studies

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Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau… in BMC Genomics (2015)

Article

Circulating tumor cells (CTC) and KRAS mutant circulating free DNA (cfDNA) detection in peripheral blood as biomarkers in patients diagnosed with exocrine pancreatic cancer

Pancreatic cancer remains one of the most difficult cancers to treat with the poorest prognosis. The key to improving survival rates in this disease is early detection and monitoring of disseminated and residu...

Julie Earl, Sandra Garcia-Nieto, Jose Carlos Martinez-Avila, José Montans… in BMC Cancer (2015)

Article

The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies

Urothelial bladder cancer is a highly heterogeneous disease. Cancer cell lines are useful tools for its study. This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lin...

Julie Earl, Daniel Rico, Enrique Carrillo-de-Santa-Pau… in BMC Genomics (2015)