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Protocol
Evolution of Cell-Type-Specific RNA Aptamers via Live Cell-Based SELEX
Live cell-based SELEX (Systematic Evolution of Ligand EXponential enrichment) is a promising approach for identifying aptamers that can selectively bind to a cell-surface receptor or recognize a particular tar...
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Article
Open AccessImported cases of cutaneous leishmaniasis in Cuba, 2017: role of human movement
Leishmaniasis is a vector-borne disease caused by several species from genus Leishmania. An increase in the number of cases related to human movement has been informed in the last years. Due to the increase of su...
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Article
Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells
Multimodal single-cell assays provide high-resolution snapshots of complex cell populations, but are mostly limited to transcriptome plus an additional modality. Here, we describe expanded CRISPR-compatible ce...
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Article
Open AccessEndothelial cell activation on 3D-matrices derived from PDGF-BB-stimulated fibroblasts is mediated by Snail1
Carcinomas, such as colon cancer, initiate their invasion by rescuing the innate plasticity of both epithelial cells and stromal cells. Although Snail is a transcriptional factor involved in the Epithelial-Mes...
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Article
Open AccessDifferential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer
Exosome production from cancer-associated fibroblasts seems to be an important driver of tumor progression. We report the first in-depth biotype characterization of ncRNAs, analyzed by Next Generation Sequenci...
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Chapter and Conference Paper
Data Augmentation in Deep Learning-Based Obstacle Detection System for Autonomous Navigation on Aquatic Surfaces
Deep learning-based frameworks have been widely used in object recognition, perception and autonomous navigation tasks, showing outstanding feature extraction capabilities. Nevertheless, the effectiveness of s...
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Article
Perianal involvement and inguinal adenitis as unusual presentation of tuberculosis
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Chapter and Conference Paper
Current Status of the OSIRIS-GTC Instrument Control System
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Chapter and Conference Paper
Improved Control Electronics for OSIRIS-GTC Commercial Tunable Filters