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  1. Article

    Open Access

    The best linear unbiased prediction (BLUP) method as a tool to estimate the lifetime risk of pancreatic ductal adenocarcinoma in high-risk individuals with no known pathogenic germline variants

    Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death in the Western world. The number of diagnosed cases and the mortality rate are almost equal as the majority of patien...

    Cristina-Marianini-Rios, María E. Castillo Sanchez… in Familial Cancer (2024)

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  2. Article

    Open Access

    The Spanish Familial Pancreatic Cancer Registry (PANGENFAM): a decade follow-up of individuals at high-risk for pancreatic cancer

    The Spanish Familial Pancreatic Cancer Registry (PANGENFAM) was established in 2009 and aims to characterize the genotype and phenotype of familial pancreatic cancer (FPC). Furthermore, an early detection scre...

    Julie Earl, Raquel Fuentes, María E. Castillo Sanchez… in Familial Cancer (2024)

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  3. No Access

    Chapter

    Cancer Stem Cells in Melanoma

    The Cancer Stem Cells (CSC) are a subpopulation of tumoral cells characterized by the ability to self-renew and to establish tumours upon transplantation, to remain quiescent for long time and to have an innat...

    Ainara Soria, Jacobo Muñoz del Toro… in Stem Cells in Cancer: Should We Believe or… (2014)