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Open AccessCorrection: Transcriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization
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Article
Open AccessImproving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach
The probiotic yeast Saccharomyces boulardii (Sb) is a promising chassis to deliver therapeutic proteins to the gut due to Sb’s innate therapeutic properties, resistance to phage and antibiotics, and high protein ...
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Article
Open AccessTranscriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization
Adaptation to alkalinization of the medium in fungi involves an extensive remodeling of gene expression. Komagataella phaffii is an ascomycetous yeast that has become an organism widely used for heterologous prot...
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Article
Open AccessExtending resolution within a single imaging frame
The resolution of fluorescence microscopy images is limited by the physical properties of light. In the last decade, numerous super-resolution microscopy (SRM) approaches have been proposed to deal with such h...
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Open AccessAuthor Correction: Enhanced stability in CH3NH3PbI3 hybrid perovskite from mechano-chemical synthesis: structural, microstructural and optoelectronic characterization
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Open AccessDebaryomyces hansenii: an old acquaintance for a fresh start in the era of the green biotechnology
The halophilic yeast Debaryomyces hansenii has been studied for several decades, serving as eukaryotic model for understanding salt and osmotic tolerance. Nevertheless, lack of consensus among different studies i...
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Open AccessEnhanced stability in CH3NH3PbI3 hybrid perovskite from mechano-chemical synthesis: structural, microstructural and optoelectronic characterization
Among the hybrid organic–inorganic perovskites MAPbX3 (MA: methyl-ammonium CH3–NH3+, X = halogen), the triiodide specimen (MAPbI3) is still the material of choice for solar energy applications. Although it is abl...
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Article
On Asymmetric Regression Models with Allowance for Temporal Dependence
Log-symmetric regression models are particularly useful when the response variable is continuous, strictly positive and asymmetric. In this paper, we proposed a class of log-symmetric regression models in the ...
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Article
Defining and combating antibiotic resistance from One Health and Global Health perspectives
Several interconnected human, animal and environmental habitats can contribute to the emergence, evolution and spread of antibiotic resistance, and the health of these contiguous habitats (the focus of the One...
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Protocol
Improving the Production of Cofactor-Containing Proteins: Production of Human Hemoglobin in Yeast
Human hemoglobin is an essential protein, whose main function as an oxygen carrier is indispensable for life. Hemoglobin is a cofactor-containing protein with heme as prosthetic group. Same as in humans, heme ...
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Article
t-Resveratrol Protects against Acute High Glucose Damage in Endothelial Cells
Postprandial hyperglycemia in diabetic and nondiabetic subjects is associated with endothelial dysfunction. Evidence shows that high glucose generates oxidative stress and a pro-inflammatory state promoting th...
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Open AccessGenome-wide analysis shows that RNase G plays a global role in the stability of mRNAs in Stenotrophomonas maltophilia
Gene expression is determined by critical processes such as RNA synthesis and degradation. Ribonucleases participate in the coordinated and differential decay of messenger RNAs. We describe a suitable method o...
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Article
Open AccessMultilevel selection of bcrABDR-mediated bacitracin resistance in Enterococcus faecalis from chicken farms
In this study we isolated 109 Enterococcus faecalis from chicken faecal samples in 6 provinces of China to investigate the prevalence and transmission mechanism of the bacitracin resistance locus bcrABDR in E. fa...
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Antimicrobial Drug Efflux Pumps in Stenotrophomonas maltophilia
Stenotrophomonas maltophilia is an emerging opportunistic pathogen with an environmental origin. One of the most cumbersome characteristics of S. maltophilia is its natural low susceptibility to different antimi...
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Prioritizing risks of antibiotic resistance genes in all metagenomes
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What is a resistance gene? Ranking risk in resistomes
In this Opinion article, Baquero and colleagues propose a hierarchical system for estimating the risks associated with genes present in environmental resistomes, by evaluating the likelihood of their introduct...
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Article
Correlation of cell growth and heterologous protein production by Saccharomyces cerevisiae
With the increasing demand for biopharmaceutical proteins and industrial enzymes, it is necessary to optimize the production by microbial fermentation or cell cultures. Yeasts are well established for the prod...
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Article
Factors Related to Anastomotic Dehiscence and Mortality After Terminal Stomal Closure in the Management of Patients with Severe Secondary Peritonitis
Management of severe secondary peritonitis (SSP) may require intestinal resections and bowel exteriorization due to an unacceptable high risk for anastomotic dehiscence (AD). Bowel exteriorization can be achie...
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Article
Open AccessPredictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants
Predicting antibiotic resistance before it emerges at clinical settings constitutes a novel approach for preventing and fighting resistance of bacterial pathogens. To analyse the possibility that novel plasmid...
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Article
Predicting antibiotic resistance
Accurately predicting the emergence of antibiotic resistance will be crucial to prolonging the clinical life of new antimicrobial molecules. Here, the authors propose methodological guidelines that should allo...
