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Open AccessImproving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach
The probiotic yeast Saccharomyces boulardii (Sb) is a promising chassis to deliver therapeutic proteins to the gut due to Sb’s innate therapeutic properties, resistance to phage and antibiotics, and high protein ...
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Article
Open AccessEngineered cell differentiation and sexual reproduction in probiotic and mating yeasts
G protein-coupled receptors (GPCRs) enable cells to sense environmental cues and are indispensable for coordinating vital processes including quorum sensing, proliferation, and sexual reproduction. GPCRs compr...