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Article
Parameter Effects on the Total Intensity of H i Ly \(\alpha \) Line for a Modeled Coronal Mass Ejection and Its Driven Shock
The combination of the H i Ly α \(\alpha \) (121.6 nm) line formation mechanis...
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Article
Open AccessDexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice
Multiple sevoflurane exposures may damage the develo** brain. The neuroprotective function of dexmedetomidine has been widely confirmed in animal experiments and human studies. However, the effect of dexmede...
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Article
Deamidation enables pathogenic SMAD6 variants to activate the BMP signaling pathway
The BMP signaling pathway plays a crucial role in regulating early embryonic development and tissue homeostasis. SMAD6 encodes a negative regulator of BMP, and rare variants of SMAD6 are recurrently found in indi...
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Article
Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
Sympathetic eruptions of solar prominences have been studied for decades, however, it is usually difficult to identify their causal links. Here, we present two failed prominence eruptions on 26 October 2022 an...
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Article
Open AccessQuantitative proteome-wide O-glycoproteomics analysis with FragPipe
Identification of O-glycopeptides from tandem mass spectrometry data is complicated by the near complete dissociation of O-glycans from the peptide during collisional activation and by the combinatorial explos...
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Article
Open AccessComparative effectiveness of sodium-glucose cotransporter-2 inhibitors for new-onset gastric cancer and gastric diseases in patients with type 2 diabetes mellitus: a population-based cohort study
To compare the risks of gastric cancer and other gastric diseases in patients with type-2 diabetes mellitus (T2DM) exposed to sodium-glucose cotransporter 2 inhibitors (SGLT2I), dipeptidyl peptidase-4 inhibito...
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Article
Axis path planning of five-axis surface machining by optimizing differential vector of the axis movement considering tool posture limits
Two rotating axes of the five-axis machine tools complicate the kinematics, which increases the difficulty of trajectory planning of five-axis CNC machining. In the process of machining a free-form surface wit...
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Article
Open AccessAutomatic Solar Flare Detection Using the Solar Disk Imager Onboard the ASO-S Mission
We present an automated solar flare detection software tool to automatically process solar observed images, detect and track solar flares, and finally compile an event catalog. It can identify and track flares...
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Article
Open AccessSpectral and Imaging Observations of a C2.3 White-Light Flare from the Advanced Space-Based Solar Observatory (ASO-S) and the Chinese H \(\alpha \) Solar Explorer (CHASE)
Solar white-light flares are characterized by an enhancement in the optical continuum, which are usually large flares (X- and M-class flares). Here, we report a small C2.3 white-light flare (SOL2022-12-20T04:1...
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Article
Open AccessDeep reinforcement learning for multi-class imbalanced training: applications in healthcare
With the rapid growth of memory and computing power, datasets are becoming increasingly complex and imbalanced. This is especially severe in the context of clinical data, where there may be one rare event for ...
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Article
Correction to: Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model
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Article
Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model
Ketamine as a glutamate receptor antagonist has a rapid, potent, and long-lasting antidepressant effect, but its specific mechanism is still not fully understood. Depression is associated with elevated levels ...
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Article
Open AccessAberrant activated Notch1 promotes prostate enlargement driven by androgen signaling via disrupting mitochondrial function in mouse
The prostate is a vital accessory gonad in the mammalian male reproductive system. With the ever-increasing proportion of the population over 60 years of age worldwide, the incidence of prostate diseases, such...
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Article
The measurement of changes in water content during hemodialysis: a non-invasive millimeter wave sensing technology
Background: Adequate hemodialysis requires not only sufficient removal of excess toxins, but also removal of water retained for the dialysis patient. There is no accurate detection technique for setting the am...
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Article
Open AccessAssessment of Self-report, Palpation, and Surface Electromyography Dataset During Isometric Muscle Contraction
Measuring muscle fatigue involves assessing various components within the motor system. While subjective and sensor-based measures have been proposed, a comprehensive comparison of these assessment measures is...
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Article
Deciphering DOM-metal binding using EEM-PARAFAC: Mechanisms, challenges, and perspectives
Dissolved organic matter (DOM) is a pivotal component of the biogeochemical cycles and can combine with metal ions through chelation or complexation. Understanding this process is crucial for tracing metal sol...
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Article
Open AccessThermo-optic epsilon-near-zero effects
Nonlinear epsilon-near-zero (ENZ) nanodevices featuring vanishing permittivity and CMOS-compatibility are attractive solutions for large-scale-integrated systems-on-chips. Such confined systems with unavoidabl...
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Article
Open AccessA Statistical Study of Solar White-Light Flares Observed by the White-Light Solar Telescope of the Lyman-Alpha Solar Telescope on the Advanced Space-Based Solar Observatory (ASO-S/LST/WST) at 360 nm
Solar white-light flares (WLFs) are those accompanied by brightenings in the optical continuum or integrated light. The White-light Solar Telescope (WST), as an instrument of the Lyman-alpha Solar Telescope (LST)...
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Article
Open AccessAdvancing green finance: a review of climate change and decarbonization
This paper comprehensively reviews the interconnections between climate change, decarbonization, and green finance. The urgency of addressing climate change and its catastrophic consequences needs to focus on ...
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Article
Unraveling the impacts of nano-scale carbon exposure on nitrogen metabolism during early seedling establishment in Zea mays L. roots
Elucidating the relationship between extraneous nano-scale carbon properties and the metabolomic response of early Zea mays L. seedling establishment roots is crucial to reveal nano-carbon regulation and nutrient...
