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Article
An evaluation model of hepatic steatosis based on CT value and serum uric acid/HDL cholesterol ratio can predict intrahepatic recurrence of colorectal cancer liver metastasis
Intrahepatic recurrence is one of the main causes of treatment failure in patients with colorectal cancer liver metastasis (CRLM). Hepatic steatosis was reported to provide fertile soil for metastasis. The eff...
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Article
Open AccessMutant KRAS-activated circATXN7 fosters tumor immunoescape by sensitizing tumor-specific T cells to activation-induced cell death
Mutant KRAS (KRASMUT) is often exploited by cancers to shape tumor immunity, but the underlying mechanisms are not fully understood. Here we report that tumor-specific cytotoxic T lymphocytes (CTLs) from KRASMUT ...
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Article
Open AccessA positive feedback circuit driven by m6A-modified circular RNA facilitates colorectal cancer liver metastasis
Liver metastasis is the leading cause of death in patients with colorectal cancer (CRC). Emerge evidence suggests that circular RNA (circRNA) is a pivotal player in cancer progression. However, its role in CRC...
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Article
Open AccessCorrection: Magnesium intake and all-cause mortality after stroke: a cohort study
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Open AccessMagnesium intake and all-cause mortality after stroke: a cohort study
Population-based studies have shown that adequate magnesium intake is associated with a lower risk of stroke and all-cause mortality. Whether adequate magnesium intake is important for reducing all-cause morta...
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Article
Open AccessNeoadjuvant chemotherapy weakens the prognostic value of the pathological tumor burden score for colorectal cancer liver metastases
The pathological tumor burden score (TBS) has been proven to be a better risk stratification tool for liver metastasis of colorectal cancer than the traditional clinical risk score (CRS). The aim of this study...
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Article
Facile synthesis of hairbrush like FeVO4@C/CC anode material with enhanced electrochemical performance for alkaline ion batteries
FeVO4 is considered to be a potential anode material for alkaline ion batteries due to its abundant resources, low price, and high specific capacity. To enhance the energy storage performance of FeVO4, carbon coa...
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Article
Cr3+ and Co2+ do** modification on electrochemical performance of LiNi0.5Mn1.5O4 for Li-ion battery
It is exactly the high potential and high energy density that makes the LiNi0.5Mn1.5O4 (LNMO) an attractive material for lithium-ion battery cathode. However, the poor cycle performance of LNMO caused by John-Tel...
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Article
Open AccessLymphovascular invasion represents a superior prognostic and predictive pathological factor of the duration of adjuvant chemotherapy for stage III colon cancer patients
Lymphovascular invasion (LVI) and perineural invasion (PNI) can indicate poor survival outcomes in colorectal cancer, but few studies have focused on stage III colon cancer. The current study aimed to confirm ...
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Article
Formation of FeVO4/ZnO n–n heterojunction with enhanced sensing properties for ethanol
The n–n heterojunction is formed at the interfaces of FeVO4 and ZnO under hydrothermal conditions to increase the mobility of electrons and to decrease the barrier of oxygen activation. The results from X-ray pow...
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Article
Open AccessPrognostic value of a novel biomarker combining DNA ploidy and tumor burden score for initially resectable liver metastases from patients with colorectal cancer
Colorectal cancer liver metastases (CRLM) has not been identified as a unified disease entity due to the differences in the severity of metastatic disease and tumor aggressiveness. A screen for specific progno...
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Article
Open AccessMolecular subtype identification and prognosis stratification by a metabolism-related gene expression signature in colorectal cancer
Metabolic reprograming have been associated with cancer occurrence and progression within the tumor immune microenvironment. However, the prognostic potential of metabolism-related genes in colorectal cancer (...
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Article
Open AccessTRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability
Resistance to chemotherapy remains the major cause of treatment failure in patients with colorectal cancer (CRC). Here, we identified TRIM25 as an epigenetic regulator of oxaliplatin (OXA) resistance in CRC. T...
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Article
Hierarchical porous LixV2O4/C anode assembled with nanoflake for high-performance lithium-ion battery
Vanadium-based oxides are considered to be a type of promising electrode materials for Li-ion batteries due to their low cost and high theoretical capacity. However, the dissolution of vanadium (V3+), low electro...
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Article
Open AccessDickkopf-related protein 1, a new biomarker for local immune status and poor prognosis among patients with colorectal liver Oligometastases: a retrospective study
It was reported that tumor-expressed dickkopf-related (DKK) proteins affect micro-environment. However, the influence of DKK1 on colorectal cancer (CRC) liver oligometastases (CRCLOM) remains unclear.
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Article
Open AccessSafety and efficacy of a modified XELOX adjuvant regimen for patients with operated stage III colon cancer: a Chinese single-center experience
A fixed 8-cycle oxaliplatin and capecitabine (XELOX) regimen has been the standard adjuvant therapy for patients with stage III colon cancer. However, completing the full-cycle of oxaliplatin is often associat...
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Article
Open AccessTotal mesorectal excision with or without preoperative chemoradiotherapy for resectable mid/low rectal cancer: a long-term analysis of a prospective, single-center, randomized trial
The preliminary results of our phase II randomized trial reported comparable functional sphincter preservation rates and short-term survival outcomes between patients undergoing total mesorectal excision (TME)...
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Article
Open AccessIs there a survival benefit from adjuvant chemotherapy for patients with liver oligometastases from colorectal cancer after curative resection?
Although colorectal oligometastases to the liver can potentially be cured with aggressive local ablation, the efficacy of adjuvant chemotherapy (ACT) for such metastasis remains unclear. The present study expl...
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Article
Electrochemical properties of Li3V2(PO4)3/C cathode materials synthesized via ethylene glycol-assisted solvothermal method
The Li3V2(PO4)3/C (LVP/C) cathode materials for lithium-ion batteries were synthesized via ethylene glycol-assisted solvothermal method. The phase composition, phase transition temperature, morphology, and fined ...
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Article
Open AccessEarly recurrence in patients undergoing curative resection of colorectal liver oligometastases: identification of its clinical characteristics, risk factors, and prognosis
Oligometastatic disease can potentially be cured when an optimal approach is performed. Early recurrence after liver resection is an intractable problem, and the clinical implications remain unknown in colorec...
