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Article
All-atom RNA structure determination from cryo-EM maps
Many methods exist for determining protein structures from cryogenic electron microscopy maps, but this remains challenging for RNA structures. Here we developed EMRNA, a method for accurate, automated determi...
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Article
Open AccessNeoadjuvant chemotherapy weakens the prognostic value of the pathological tumor burden score for colorectal cancer liver metastases
The pathological tumor burden score (TBS) has been proven to be a better risk stratification tool for liver metastasis of colorectal cancer than the traditional clinical risk score (CRS). The aim of this study...
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Article
Open AccessImprovement of cryo-EM maps by simultaneous local and non-local deep learning
Cryo-EM has emerged as the most important technique for structure determination of macromolecular complexes. However, raw cryo-EM maps often exhibit loss of contrast at high resolution and heterogeneity over t...
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Article
Open AccessModel building of protein complexes from intermediate-resolution cryo-EM maps with deep learning-guided automatic assembly
Advances in microscopy instruments and image processing algorithms have led to an increasing number of cryo-electron microscopy (cryo-EM) maps. However, building accurate models into intermediate-resolution EM...
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Article
The HDOCK server for integrated protein–protein docking
The HDOCK server (http://hdock.phys.hust.edu.cn/) is a highly integrated suite of homology search, template-based modeling, structure prediction, macromolecular do...
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Article
Visual test for the presence of the illegal additive ethyl anthranilate by using a photonic crystal test strip
A test strip has been developed for the rapid detection of the illegal additive ethyl anthranilate (EA) in wine. The detection scheme is based on a combination of photonic crystal based detection and molecular...
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Article
Erratum to: Distribution of isotopes and chemicals in precipitation in Shule River Basin, northwestern China: an implication for water cycle and groundwater recharge
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Article
Distribution of isotopes and chemicals in precipitation in Shule River Basin, northwestern China: an implication for water cycle and groundwater recharge
The distribution of stable isotopes and ions in precipitation in the Shule River Basin, northwestern China, were investigated to understand the regional water cycle and precipitation input to groundwater recha...
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Article
Petroleum pollution and evolution of water quality in the Malian River Basin of the Longdong Loess Plateau, Northwestern China
The possible sources of water pollution and the evolution of water quality in the Malian River Basin of China’s Longdong Loess Plateau were studied based on chemical analysis. Concentrations of major chemicals...