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  1. No Access

    Article

    All-atom RNA structure determination from cryo-EM maps

    Many methods exist for determining protein structures from cryogenic electron microscopy maps, but this remains challenging for RNA structures. Here we developed EMRNA, a method for accurate, automated determi...

    Tao Li, Jiahua He, Hong Cao, Yi Zhang, Ji Chen, Yi **ao in Nature Biotechnology (2024)

  2. Article

    Open Access

    Neoadjuvant chemotherapy weakens the prognostic value of the pathological tumor burden score for colorectal cancer liver metastases

    The pathological tumor burden score (TBS) has been proven to be a better risk stratification tool for liver metastasis of colorectal cancer than the traditional clinical risk score (CRS). The aim of this study...

    Leen Liao, Hui Sun, Jiahua He, Yujun Liu, Zhizhong Pan, **aojun Wu in BMC Surgery (2023)

  3. Article

    Open Access

    Improvement of cryo-EM maps by simultaneous local and non-local deep learning

    Cryo-EM has emerged as the most important technique for structure determination of macromolecular complexes. However, raw cryo-EM maps often exhibit loss of contrast at high resolution and heterogeneity over t...

    Jiahua He, Tao Li, Sheng-You Huang in Nature Communications (2023)

  4. Article

    Open Access

    Model building of protein complexes from intermediate-resolution cryo-EM maps with deep learning-guided automatic assembly

    Advances in microscopy instruments and image processing algorithms have led to an increasing number of cryo-electron microscopy (cryo-EM) maps. However, building accurate models into intermediate-resolution EM...

    Jiahua He, Peicong Lin, Ji Chen, Hong Cao, Sheng-You Huang in Nature Communications (2022)

  5. No Access

    Article

    The HDOCK server for integrated protein–protein docking

    The HDOCK server (http://hdock.phys.hust.edu.cn/) is a highly integrated suite of homology search, template-based modeling, structure prediction, macromolecular do...

    Yumeng Yan, Huanyu Tao, Jiahua He, Sheng-You Huang in Nature Protocols (2020)

  6. No Access

    Article

    Visual test for the presence of the illegal additive ethyl anthranilate by using a photonic crystal test strip

    A test strip has been developed for the rapid detection of the illegal additive ethyl anthranilate (EA) in wine. The detection scheme is based on a combination of photonic crystal based detection and molecular...

    Yi Zhang, Zhenkai **, Qingsong Zeng, Yanmei Huang, Hang Gu, Jiahua He in Microchimica Acta (2019)

  7. Article

    Erratum to: Distribution of isotopes and chemicals in precipitation in Shule River Basin, northwestern China: an implication for water cycle and groundwater recharge

    Wei Zhao, **zhu Ma, Chunjie Gu, Shi Qi, Gaofeng Zhu, Jiahua He in Journal of Arid Land (2017)

  8. No Access

    Article

    Distribution of isotopes and chemicals in precipitation in Shule River Basin, northwestern China: an implication for water cycle and groundwater recharge

    The distribution of stable isotopes and ions in precipitation in the Shule River Basin, northwestern China, were investigated to understand the regional water cycle and precipitation input to groundwater recha...

    Wei Zhao, **zhu Ma, Chunjie Gu, Shi Qi, Gaofeng Zhu, Jiahua He in Journal of Arid Land (2016)

  9. No Access

    Article

    Petroleum pollution and evolution of water quality in the Malian River Basin of the Longdong Loess Plateau, Northwestern China

    The possible sources of water pollution and the evolution of water quality in the Malian River Basin of China’s Longdong Loess Plateau were studied based on chemical analysis. Concentrations of major chemicals...

    **zhu Ma, Feng Pan, Jiahua He, Lihua Chen, Su**g Fu in Environmental Earth Sciences (2012)