4,010 Result(s)
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Jian-** Guo
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Article
Study on Acoustic Emission and Crack Propagation Characteristics of Single-Fissured Sandstone with Different Angles Under Uniaxial Compression
The uniaxial compression tests are conducted on single-fissured sandstone with different angles, and the effect of fissure angle (β) on mechanical properties, acoustic emission (AE) features, crack propagation ch...
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Recurrent neural network robust curvature tracking control of tendon-driven continuum manipulators with simultaneous joint stiffness regulation
Continuum manipulators, despite their prominent flexibility and compliance, possess relatively low inherent stiffness and weak load capacity. Realizing simultaneous curvature tracking control and joint stiffne...
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
Major depressive disorder, a prevalent and severe psychiatric condition, necessitates development of new and fast-acting antidepressants. Genetic suppression of astrocytic inwardly rectifying potassium channel...
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Open AccessNicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying mechanism of nicotinate-curcumin (NC) in the treatment of NASH remain unce...
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Open AccessAnalysis of tumor microenvironment alterations in partially responsive rectal cancer patients treated with neoadjuvant chemoradiotherapy
Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy ...
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Open AccessPET/CT deep learning prognosis for treatment decision support in esophageal squamous cell carcinoma
The clinical decision-making regarding choosing surgery alone (SA) or surgery followed by postoperative adjuvant chemotherapy (SPOCT) in esophageal squamous cell carcinoma (ESCC) remains controversial. We aim ...
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Monitoring and warning for ammonia nitrogen pollution of urban river based on neural network algorithms
Ammonia nitrogen (AN) pollution frequently occurs in urban rivers with the continuous acceleration of industrialization. Monitoring AN pollution levels and tracing its complex sources often require large-scale...
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Open AccessCorrection: Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease
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Open AccessA multi-kingdom collection of 33,804 reference genomes for the human vaginal microbiome
The human vagina harbours diverse microorganisms—bacteria, viruses and fungi—with profound implications for women’s health. Genome-level analysis of the vaginal microbiome across multiple kingdoms remains limi...
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Open AccessA N–CoSe/CoSe2–C@Cu hierarchical architecture as a current collector-integrated anode for potassium-ion batteries
The highly reversible insertion/extraction of large-radius K+ into electrode materials remains a tough goal, especially for conversion-type materials. Herein, we design a current collector-integrated electrode (N...
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Numerical simulation and experimental investigation of manufacturing route of directional casting super slab
We proposed a new technique route of directional solidification for the manufacture of super slab. A 7-t laboratory-scale thick slab was casted and characterised for trial. To further understand the process, t...
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Charge-controlled compositional/microstructural regulations and electrochemical actuation performance of bulk nanoporous Ni-Pd alloys
Bulk nanoporous (np) metallic actuators have attracted increasing attention due to their large strain and low stimulation voltage. However, studies focusing upon the combined effect of composition and structur...
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Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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Phase Equilibria of Ti-Bearing Electric Furnace Slags in Air at 1400 °C in CaO–MgO–SiO2–13 wt pct Al2O3–50 wt pct TiO2 System
Phase equilibria for the CaO–MgO–SiO2–13 wt pct Al2O3–50 wt pct TiO2 system were experimentally investigated at 1400 °C in air atmosphere, employing the high-temperature equilibration and quenching method. Seven ...
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Open AccessAssociation analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson’s disease
Cognitive impairment is a common non-motor symptom of Parkinson’s disease (PD). The apolipoprotein E (APOE) ε4 genotype increases the risk of Alzheimer’s disease (AD). However, the effect of APOEε4 on cognitiv...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Open AccessA Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex
This study aimed to identify possible pathogenic genes in a 90-member family with a rare combination of multiple neurodegenerative disease phenotypes, which has not been depicted by the known neurodegenerative...
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Open AccessStructure of cryptophyte photosystem II–light-harvesting antennae supercomplex
Cryptophytes are ancestral photosynthetic organisms evolved from red algae through secondary endosymbiosis. They have developed alloxanthin-chlorophyll a/c2-binding proteins (ACPs) as light-harvesting complexes (...
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Experimental quantum computational chemistry with optimized unitary coupled cluster ansatz
Quantum computational chemistry has emerged as a potential application of quantum computing. Hybrid quantum-classical computing methods, such as variational quantum eigensolvers, have been designed as promisin...
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Open AccessDysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive ages. Our previous study has implicated a possible link between RNA editing and PCOS, yet the actual role of R...
