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Article
Deep learning-based method for reducing the number of transmitting coils in logging while drilling tool
Electromagnetic wave logging while drilling (LWD) technology is an important tool for evaluation of formation oil and gas content. It generally adopts multi-transmitter–receiver coil system structure and the s...
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Article
High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1
Bladder outlet obstruction (BOO) results in significant fibrosis in the chronic stage and elevated bladder pressure. Piezo1 is a type of mechanosensitive (MS) channel that directly responds to mechanical stimu...
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Article
Open AccessSMAD4 depletion contributes to endocrine resistance by integrating ER and ERBB signaling in HR + HER2− breast cancer
Endocrine resistance poses a significant clinical challenge for patients with hormone receptor-positive and human epithelial growth factor receptor 2-negative (HR + HER2−) breast cancer. Dysregulation of estro...
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Article
A molecularly imprinted ratiometric fluorescent sensor for visual detection of 1-naphthol based on fluorescence-enhanced CdTeS QDs via APTES modification
CdTeS quantum dots (CdTeS QDs) were synthesized using the hydrothermal method and subsequently modified with (3-aminopropyl)triethoxysilane (APTES). This modification resulted in a significant enhancement of t...
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Article
Open AccessAdditive effect of admission hyperglycemia on left ventricular stiffness in patients following acute myocardial infarction verified by CMR tissue tracking
Stress hyperglycemia occurs frequently in patients following acute myocardial infarction (AMI) and may aggravate myocardial stiffness, but relevant evidence is still lacking. Accordingly, this study aimed to e...
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Article
Open AccessStructure of cryptophyte photosystem II–light-harvesting antennae supercomplex
Cryptophytes are ancestral photosynthetic organisms evolved from red algae through secondary endosymbiosis. They have developed alloxanthin-chlorophyll a/c2-binding proteins (ACPs) as light-harvesting complexes (...
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Article
Open AccessDevelopment of Vogt–Koyanagi–Harada disease-like uveitis during treatment by anti-programmed death-1 antibody: a case report
Several immune checkpoint inhibitors (ICIs) have been linked to the occurrence of Vogt-Koyanagi-Harada disease (VKHD)-like uveitis. Among the ICIs, there has been no report of immune-related adverse events (ir...
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Article
Open AccessAssociation of depressive symptoms and sleep disturbances with survival among US adult cancer survivors
Depression and sleep disturbances are associated with increased risks of various diseases and mortality, but their impacts on mortality in cancer survivors remain unclear. The objective of this study was to ch...
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Article
Open AccessIdentification of an HLA-A*11:01-restricted neoepitope of mutant PIK3CA and its specific T cell receptors for cancer immunotherapy targeting hotspot driver mutations
Hotspot driver mutations presented by human leukocyte antigens might be recognized by anti-tumor T cells. Based on their advantages of tumor-specificity and immunogenicity, neoantigens derived from hotspot mut...
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Article
Prognosis prediction of high grade serous adenocarcinoma based on multi-modal convolution neural network
The prognostic analysis for high grade serous adenocarcinoma (HGSC) holds significant clinical importance. However, current prognostic analysis primarily relies on statistical techniques like logistic regressi...
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Article
Characterization and value-added applications of natural cellulose fibers derived from cow dung in cementitious composites
Cow dung possesses potential agricultural and energy value but is often regarded as waste and underutilized in most cases. This wastage of resources not only poses a challenge to agricultural sustainability bu...
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Article
Open AccessEstablishing a machine learning model based on dual-energy CT enterography to evaluate Crohn’s disease activity
The simplified endoscopic score of Crohn’s disease (SES-CD) is the gold standard for quantitatively evaluating Crohn’s disease (CD) activity but is invasive. This study aimed to develop and validate a machine ...
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Article
Heterobimetallic [NiCo] integration in a hydrogenase mimic for boosting light-driven hydrogen evolution in CaTiO3
Light-drive hydrogen production using titanium-based perovskite is one sustainable way to reduce current reliance on fossil fuels, but its wide applications are still limited by high electron–hole recombinatio...
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Article
Open AccessClinical and epidemiological characteristics of 96 pediatric human metapneumovirus infections in Henan, China after COVID-19 pandemic: a retrospective analysis
In the aftermath of the COVID-19 pandemic, there has been a surge in human metapneumovirus (HMPV) transmission, surpassing pre-epidemic levels. We aim to elucidate the clinical and epidemiological characterist...
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Article
Open AccessQuantitative analysis and stochastic modeling of osteophyte formation and growth process on human vertebrae based on radiographs: a follow-up study
Osteophytes are frequently observed in elderly people and most commonly appear at the anterior edge of the cervical and lumbar vertebrae body. The anterior osteophytes keep develo** and will lead to neck/bac...
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Article
Photo-electric properties of ultra-thin cuprous oxide films prepared by electrodeposition
Electrodeposition of cuprous oxide thin film is becoming a more and more important method, but higher content of Cu2+ and uneven grain size in cuprous oxide thin films fabricated by direct current (DC) electrodep...
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Article
Open AccessSingle cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification
Head and neck squamous cell carcinoma (HNSCC) is characterized by high recurrence or distant metastases rate and the prognosis is challenging. There is mounting evidence that tumor-infiltrating B cells (TIL-Bs...
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Article
Open AccessIntegrating bulk and single-cell sequencing data to construct a Scissor+ dendritic cells prognostic model for predicting prognosis and immune responses in ESCC
Esophageal squamous cell carcinoma (ESCC) is characterized by molecular heterogeneity with various immune cell infiltration patterns, which have been associated with therapeutic sensitivity and resistance. In ...
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Article
Open AccessMETTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis
The regulatory role of N6-methyladenosine (m6A) modification in the onset and progression of cancer has garnered increasing attention in recent years. However, the specific role of m6A modification in pulmonar...
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Article
Open AccessCPDC-MFNet: conditional point diffusion completion network with Muti-scale Feedback Refine for 3D Terracotta Warriors
Due to the antiquity and difficulty of excavation, the Terracotta Warriors have suffered varying degrees of damage. To restore the cultural relics to their original appearance, utilizing point clouds to repair...
