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Article
Fluid resuscitation in children with severe infection and septic shock: a systematic review and meta-analysis
This study aimed to evaluate the current evidence on various aspects of fluid therapy such as type, volume, and timing of fluid bolus administration in children with septic shock. Systematic review and meta-an...
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Article
Refining Ventilation During Neonatal Resuscitation Using Ventilator: Time for a Well-Designed Clinical Study!
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Article
Infant Pulmonary Function Tests in Children with Airway Anomalies and Correlation with Bronchoscopy Findings
To evaluate the role infant pulmonary function tests (Tidal Breathing Flow Volume Loops, TBFVL) in children with airway anomalies and to correlate the TBFVL so obtained with bronchoscopy findings.
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Article
Furosemide stress test to predict acute kidney injury progression in critically ill children
Furosemide stress test (FST) is a novel functional biomarker for predicting severe acute kidney injury (AKI); however, pediatric studies are limited.
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Article
Development and Validation of a Weight Estimation Tool for Acutely Ill Children Who Cannot be Weighed
To develop and validate weight estimation tools using mid upper arm circumference (MUAC) and body length, and determine accuracy and precision of Broselow tape in children 6 mo to 15 y of age.
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Article
Long-Term Outcomes of Survivors of COVID-19 with Moderate to Severe Infection and Children with Multisystem Inflammatory Syndrome or MIS-C
The study aims to evaluate the long-term outcomes − functional, pulmonary and non-pulmonary (other organs) − in children hospitalized with COVID-19 infection or with Multisystem inflammatory syndrome (MIS-C) a...
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Article
Validation of a Clinical Tool to Predict Neurological Outcomes in Critically Ill Children—A Prospective Observational Study
To evaluate the performance of the empiric tool by Gupta et al. in predicting neurological outcomes in children admitted to the pediatric intensive care unit (PICU) and to evaluate the association of biomarker...
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Article
Comparison of Protocol-Based Continuous and Intermittent Tube Feeding in Mechanically Ventilated Critically Ill Children – An Open Label Randomized Controlled Trial
To compare the time taken to reach the target calories and proteins by protocol based “continuous tube feeding (CTF)” and “intermittent tube feeding (ITF)” in critically ill children.
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Article
Utility of Inferior Vena Cava Distensibility and Respiratory Variation in Peak Aortic Blood Flow Velocity to Predict Fluid Responsiveness in Children with Shock
To evaluate the sensitivity and specificity of inferior vena cava (IVC) distensibility index (∆IVC) and respiratory variation in peak aortic blood flow velocity (∆Vpeak) to predict fluid responsiveness in vent...
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Article
Evaluation of Changes in Quadriceps Femoris Muscle in Critically III Children Using Ultrasonography
To measure changes in muscle thickness and echogenicity, reflecting muscle bulk and quality, respectively, of quadriceps femoris (QF), in critically ill children.
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Article
Feasibility and Efficacy of Sustained Low-Efficiency Dialysis in Critically Ill Children with Severe Acute Kidney Injury
To examine the feasibility, efficacy, and safety of sustained low-efficiency dialysis (SLED) in hemodynamically unstable, critically ill children.
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Article
Advances in Shock Management and Fluid Resuscitation in Children
Shock in children is associated with significant mortality and morbidity, particularly in resource-limited settings. The principles of management include early recognition, fluid resuscitation, appropriate ino...
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Article
Quality Improvement Initiative to Improve Initiation and Acceptability of Noninvasive Ventilation in Critically Ill Children
To evaluate if the use of a quality improvement (QI) initiative improves initiation and acceptability of noninvasive ventilation (NIV) in critically ill children with respiratory distress.
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Article
Outcomes of Children with Unoperated Congenital Heart Disease Admitted to PICU—A Single-Center Experience
To evaluate the outcomes of children with congenital heart disease (CHD) awaiting surgery admitted to a pediatric intensive care unit (PICU) with acute illness.
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Article
Extracellular Histones—Friend or Foe?
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Article
Role of Breathing Exercises in Asthma—Yoga and Pranayama
Asthma is a chronic airway inflammatory disease that results from a complex interplay of genetic, environmental, and lifestyle factors. There is no cure for asthma, and the management is usually as per publish...
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Article
Clinical and Laboratory Parameters Associated with Septic Myocardial Dysfunction in Children with Septic Shock
The authors’ objective was to determine the association of clinical and laboratory parameters at admission with septic myocardial dysfunction (SMD) in children with septic shock. A chart review of children age...
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Article
Dexmedetomidine vs Midazolam for Sedation in Mechanically Ventilated Children: A Randomized Controlled Trial
There is a paucity of data on use of dexmedetomidine as a sedative agent in mechanically ventilated children.
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Article
Acute Kidney Injury in Dengue – Not Unprecedented
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Article
COVID-19 in Children: Clinical Approach and Management
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health crisis threatening humanity at this point in time. Transmission of the infection occurs by inha...