5 Result(s)
within
Igor Theurl
Infectious Diseases
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Article
Evaluating the clinical utility and sensitivity of SARS-CoV-2 antigen testing in relation to RT-PCR Ct values
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Article
Open AccessIron deficiency or anemia of inflammation?
Iron deficiency and immune activation are the two most frequent causes of anemia, both of which are based on disturbances of iron homeostasis. Iron deficiency anemia results from a reduction of the body’s iron...
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Article
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver
Damaged erythrocytes accumulate in various pathological conditions, such as hemolytic anemia, anemia of inflammation, and sickle cell disease. In mice challenged with damaged erythorcytes, a monocyte subset mi...
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Article
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
Macrophages are abundant in atherosclerotic plaques and are a pivotal cell type in plaque formation and progression. But how do they get there? Filip Swirski and his colleagues show that, contrary to most prev...
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Article
Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1
Hereditary hemochromatosis and transfusional iron overload are frequent clinical conditions associated with progressive iron accumulation in parenchymal tissues, leading to eventual organ failure. We have disc...
