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Article
Determination of Methylphosphonic Acid and Alkyl Methylphosphonic Acid Esters in Soils by Liquid Chromatography–High-Resolution Mass Spectrometry
A method has been optimized for simultaneous extraction of ethyl methylphosphonic acid ester (EMPA), isopropyl methylphosphonic acid ester (IPMPA), isobutyl methylphosphonic acid ester (IBMPA), pinacolyl methy...
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Article
Determination of Hydrolytic Transformation Products of Sesquimustards in Water by High Resolution Liquid Chromatography/Mass Spectrometry
An approach to the determination of five sesquimustard markers, namely, bis(2-hydroxyethylthio)methane (BHETM), 1,2-bis(2-hydroxyethylthio)ethane (BHETE), 1,3-bis(2-hydroxyethylthio)-n-propane (BHETPr), 1,4-bis(2...
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Article
Determination of Nitrogen Mustard Metabolites in Urine Using High-Performance Liquid Chromatography–High-Resolution Mass Spectrometry
Liquid chromatography–high-resolution mass spectrometry that combines the capabilities of highly selective separation of mixtures under study, valid detection of unknown substances, and high sensitivity is wid...
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Chapter and Conference Paper
“Interdisciplinary Transfer” in Creating an Urban Governance Ecosystem in Digitalization
The authors attempt to apply the scientific method of “interdisciplinary transfer” (“transfer method”) to study the competitiveness of enterprises in the ecosystem of urban management and apply principles and ...
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Article
Determination of p-Methoxyphenacyl Bromide Derivatives of Alkylmethylphosphonic Acids in Urine Using Gas Chromatography with High-Resolution Mass Spectrometric Detection
We developed a method for determining ethyl methylphosphonic, isopropyl methylphosphonic, isobutyl methylphosphonic, and pinacolyl methylphosphonic acids in human urine using gas chromatography with high-resol...
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Article
Characteristics of a High-Resolution Mass Spectrum of an Adduct of 2-(Diethylamino)Ethylthiol with a Dipeptide (Cys–Pro)
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Article
Identification of Adducts of O-Isopropylmethylphosphonic and O-Cyclohexylmethylphosphonic Acids with a Tripeptide (Tyr-Thr-Lys) in Human Plasma by Liquid Chromatography–Mass Spectrometry
We proposed a method for determining the presence of trace amounts of adducts of isopropylmethylphosphonic acid (IMPA) and cyclohexylmethylphosphonic acid (CMPA), biomarkers of exposure to sarin and cyclosarin...
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Article
p-Methoxyphenacyl Bromide as a Versatile Reagent for the Determination of Alkylphosphonic and Alkylmethylphosphonic Acids by High-Performance Liquid and Gas Chromatography with Mass Spectrometric Detection
A multipurpose reagent, p-methoxyphenacyl bromide, is proposed for the derivatization of polar products of the degradation (markers) of nerve agents, which allows their determination by high-performance liquid ch...
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Article
Phosphorylation of Tyrosine and Tyr-Thr-Lys Tripeptide with Cyclohexylmethyl- and (Deuteromethyl)phosphonochloridates
Methods for phosphorylation of tyrosine and Tyr-Thr-Lys tripeptide with cyclohexylmethyl(deuteromethyl)phosphonochloridates have been developed. These products can be used as reference compounds in the analysi...
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Article
Synthesis of the Tripeptides Tyr-Thr-Lys Phosphorylated with Isopropyl Methyl- and (Deuteromethyl)phosphonochloridates as Reference Standards for the Analysis of Biomedical Samples
A procedure for the phosphorylation of the tripeptide Tyr-Thr-Lys with isopropyl methyl- or (deuteromethyl)phosphonochloridate is developed. The phosphorylated tripeptides are intended for use as reference sta...
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Article
Selection of Recording Conditions and Study of Fragmentation of a Peptide Biomarker of Sarin by High-Performance Liquid Chromatography–High-Resolution Mass Spectrometry
The identification of protein biomarkers of chemical warfare agents involves their reliable detection in the blood plasma at trace levels. This is a challenging task in the modern liquid chromatography–mass sp...
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Article
Determination of Methylphosphonic Acid in Human Blood Plasma by High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Using high-performance liquid chromatography combined with tandem mass spectrometric detection, an approach has been developed for the determination of the most stable nerve agent biomarker, methylphosphonic a...
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Article
Determination of 2-chlorovinylarsonous acid and 2-chlorovinylarsonic acid in water by capillary electrophoresis with direct spectrophotometric detection
An approach for determining 2-chlorovinylarsonous acid and 2-chlorovinylarsonic acid (decomposition products of such blister agent as lewisite) in water by capillary zone electrophoresis was proposed. The cond...
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Article
Narcotic substances of natural origin and methods of their determination
The main representatives of narcotic substances of natural origin are considered. Methodological solutions used in their screening, identification, and quantitative determination in raw materials, dosage forms...
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Article
Determination of the hydrolysis products of nerve agents in natural waters by liquid chromatography–mass spectrometry
An approach to the determination of markers of the application of four nerve agents, S-(2-diethylaminoethyl)methylphosphonothioate, S-(2-diisopropylaminoethyl)methylphosphonothioate, bis(2N,N-diethylaminoethyl)di...
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Article
Fragment methods for IR spectrum calculations of organophosphorus compounds
For highly toxic organophosphorus compounds on the limiting lists of the International Chemical Weapons Ban Treaty, fragment methods may be used for calculating their IR vibrational spectra; this is shown for ...
