-
Article
Novel Adsorbents for the Determination of Amino Acids in Soil Extracts by Hydrophilic Interaction Liquid Chromatography with Mass Spectrometric Detection
Adsorbents based on various substrates—silica and a copolymer of styrene with divinylbenzene—are developed for the determination of amino acids by hydrophilic interaction liquid chromatography—mass spectrometr...
-
Article
Novel Mixed-Mode Adsorbents for HPLC Based on Different Substrates Modified with Eremomycin
New adsorbents based on silica and polystyrene–divinylbenzene (PS–DVB) for hydrophilic interaction liquid chromatography (HILIC) with eremomycin in functional layers were obtained. The chromatographic properti...
-
Article
Extraction of Terpenes of Common Juniper Greenery Under Sub- and Supercritical Conditions
The efficiency of the extraction of the terpene fraction from the greenery of common juniper (Juniperus communis L.) by sub- and supercritical extraction methods is compared with the efficiency of conventional me...
-
Article
Aqueous Propylene Glycol Extracts from Medicinal Plants: Chemical Composition, Antioxidant Activity, Standardization, and Extraction Kinetics
Aqueous propylene glycol extracts from medicinal plants are commonly used as active ingredients in production of medicine and beauty products for external application. In the scientific literature, however, th...
-
Article
A Novel Adsorbent for Hydrophilic Chromatography Based on Silica Modified by the Ugi Reaction
New stationary phases for hydrophilic chromatography (HILIC) with functional layers formed by the multicomponent Ugi reaction have been obtained. Acetone, glycolic acid, ethyl isocyanacetate, and 3‑aminopropyl...
-
Article
Standardization of P. ginseng and P. quinquefolius Root Extracts by HPLC-MS
We develop a method on the basis of high-performance liquid phase chromatography–mass spectrometry (HPLC-MS) for determination of triterpene glycosides in ginseng extracts. In contrast to procedures based on H...
-
Article
Identification of Adducts of O-Isopropylmethylphosphonic and O-Cyclohexylmethylphosphonic Acids with a Tripeptide (Tyr-Thr-Lys) in Human Plasma by Liquid Chromatography–Mass Spectrometry
We proposed a method for determining the presence of trace amounts of adducts of isopropylmethylphosphonic acid (IMPA) and cyclohexylmethylphosphonic acid (CMPA), biomarkers of exposure to sarin and cyclosarin...
-
Article
Determination of Eleutheroside B and Eleutheroside E in Extracts from Eleutherococcus senticosus by Liquid Chromatography/Mass Spectrometry
Eleutherococcus senticosus is a plant with medicinal properties due to the presence of glycosides, called eleutherosides А, В and В1, C, D, E, and F, in its roots and rhizomes. In this paper, a procedure for the ...
-
Article
Study of Polyphenol Components in Extracts of Arctic Brown Algae of Fucus vesiculosus Type by Liquid Chromatography and Mass-Spectrometry
The extraction of polyphenol component of arctic brown algae of the Fucus vesiculosus type and the subsequent fractionation of the extract by column chromatography on a Sephadex LH-20 adsorbent are carried out. T...
-
Article
Structural Characterization of Triterpene Saponins from Manchurian Aralia by High Resolution Liquid Chromatography–Mass Spectrometry
The mass-spectrometric characteristics of triterpene saponins from Manchurian aralia were studied using high-performance liquid chromatography in combination with high-resolution mass-spectrometric detection. ...
-
Article
New Approaches to the Determination and Group Identification of Physiologically Active Compounds in Plant Materials and Commercial Products by High-Performance Liquid Chromatography–Mass Spectrometry
An overview of methods for the target determination of physiologically active components of various plants: rosavin, rosarin, and salidroside from Rhodiola rosea; ginsenosides Rb1, Rg1, Rf, and Re from the Asian ...
-
Article
Selection of Recording Conditions and Study of Fragmentation of a Peptide Biomarker of Sarin by High-Performance Liquid Chromatography–High-Resolution Mass Spectrometry
The identification of protein biomarkers of chemical warfare agents involves their reliable detection in the blood plasma at trace levels. This is a challenging task in the modern liquid chromatography–mass sp...
-
Article
Simultaneous Determination of Wogonin, Scutellarin, Baicalin, and Baicalein in Extracts from Scutellariae Baicalensis by High-Performance Liquid Chromatography with Tandem Mass Spectrometry
Scutellariae baicalensis is one of the most popular herb in the traditional Chinese medicine. It is used for the treatment of inflammatory process, hypertension, cardiovascular diseases, and also in the treatment...
-
Article
Obtaining Tritium-Labeled Amikacin and Its Adsorption Immobilization on Functionalized Nanodiamonds
The effect of the chemical nature of the surface of detonation nanodiamond on the adsorption of an antibiotic is revealed with the help of tritium-labeled amikacin. It is found that nanodiamonds with a carboxy...
-
Article
Determination of Methylphosphonic Acid in Human Blood Plasma by High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Using high-performance liquid chromatography combined with tandem mass spectrometric detection, an approach has been developed for the determination of the most stable nerve agent biomarker, methylphosphonic a...
-
Article
Time-Efficient LC/MS/MS Determination of Low Concentrations of Methylphosphonic Acid
A time-efficient protocol for quantification of methylphosphonic acid (MPA), a final hydrolysis product of nerve agents in aqueous environments, via liquid chromatography mass spectrometry is described. Chroma...
-
Article
Quantitative analysis of a multicomponent system for liquid chromatography–mass spectrometry determination of diosgenin, dioscin and protodioscin in plant extracts of Tribulus terrestris
An approach for the simultaneous determination of dioscin, protodioscin, and diosgenin in plant extracts by the liquid chromatography–mass spectrometry method with detection limits from 5 to 20 ng mL–1 is develop...
-
Article
Determination of 2-chlorovinylarsonous acid and 2-chlorovinylarsonic acid in water by capillary electrophoresis with direct spectrophotometric detection
An approach for determining 2-chlorovinylarsonous acid and 2-chlorovinylarsonic acid (decomposition products of such blister agent as lewisite) in water by capillary zone electrophoresis was proposed. The cond...
-
Article
Application of high performance liquid chromatography-tandem mass spectrometry for detection of melittin, a characteristic peptide of bee venom
Bee venom is widely used for the manufacturing of cosmetics and pharmaceuticals. A procedure for the detection of melittin, a characteristic component of bee venom, based on high performance liquid chromatogra...
-
Article
Simultaneous determination of ginsenosides by high-performance liquid chromatography with tandem mass spectrometry detection
An approach to the simultaneous registration of ginsenosides in herbal extracts and commercial products was developed on the basis of liquid chromatography/mass spectrometry. The approach was validated for fou...
