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Article
Genetic characteristics of a novel HIV-1 recombinant lineage (CRF103_01B) and its prevalence in northern China
During the routine surveillance of HIV-1 pretreatment drug resistance in Bei**g, five men who have sex with men (MSM) and a woman were observed to get infected by newly identified CRF103_01B strain. To elucid...
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Article
Open AccessIncidence and risk factors of hypertriglyceridemia in males with human immunodeficiency virus who are treated with combination antiretroviral therapy: a retrospective cohort study
Hypertriglyceridemia is associated with subclinical atherosclerosis and vascular inflammation even when low-density lipoprotein cholesterol levels are normal. However, few cohort studies on hypertriglyceridemi...
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Article
Open AccessCRF07_BC is associated with slow HIV disease progression in Chinese patients
HIV subtypes convey important epidemiological information and possibly influence the rate of disease progression. In this study, HIV disease progression in patients infected with CRF01_AE, CRF07_BC, and subtyp...
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Article
Open AccessHigh-Index Faceted Nanocrystals as Highly Efficient Bifunctional Electrocatalysts for High-Performance Lithium–Sulfur Batteries
High-index faceted Fe2O3 nanocrystals with abundant unsaturated Fe sites not only have strong adsorption capacity to anchor LiPSs but also have super...
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Article
Open AccessHuman umbilical cord mesenchymal stem cell transfusion in immune non-responders with AIDS: a multicenter randomized controlled trial
We examined the safety and efficacy of human umbilical cord mesenchymal stem cell (hUC-MSC) infusion for immune non-responder (INR) patients with chronic HIV-1 infection, who represent an unmet medical need ev...
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Article
High levels of circulating GM-CSF+CD4+ T cells are predictive of poor outcomes in sepsis patients: a prospective cohort study
Granulocyte colony-stimulating factor (GM-CSF), produced by CD4+ T cells, has recently been implicated in the pathogenesis of inflammatory diseases, such as multiple sclerosis and juvenile arthritis. However, the...
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Article
Open AccessLow expression of CXCR1/2 on neutrophils predicts poor survival in patients with hepatitis B virus-related acute-on-chronic liver failure
Polymorphonuclear neutrophils (PMNs) and proinflammatory cytokines have been implicated in the pathogenesis of acute-on-chronic liver failure (ACLF). But the utility of CXC chemokine receptor expression on PMN...
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Article
Complement 5a receptor-mediated neutrophil dysfunction is associated with a poor outcome in sepsis
Complement 5a (C5a) has been implicated in the pathogenesis of sepsis by inducing the functional impairment of neutrophils; however, the utility of C5a receptors (C5aRs; C5aR and C5L2) as biomarkers for the ma...
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Article
The role of neutrophils in the development of liver diseases
Liver disease encompasses a wide variety of liver conditions, including liver failure, liver cirrhosis and a spectrum of acute and chronic hepatitis, such as alcoholic, fatty, drug, viral and chronic hepatitis...