13 Result(s)
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Open AccessUnderstanding lactate in the development of Hepatitis B virus-related hepatocellular carcinoma
Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans. Chronic hepatitis B (CHB) infection is associated with an increased risk of hepatic decompensati...
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Open AccessOccurrence of some common carbapenemase genes in carbapenem-resistant Klebsiella pneumoniae isolates collected from clinical samples in Tabriz, northwestern Iran
This study aimed to evaluate the antibiotic resistance patterns and prevalence of carbapenemase genes in Klebsiella pneumoniae isolates in different clinical samples from Tabriz city, northwestern Iran.
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Article
Open AccessCRISPR–Cas system to discover host-virus interactions in Flaviviridae
The Flaviviridae virus family members cause severe human diseases and are responsible for considerable mortality and morbidity worldwide. Therefore, researchers have conducted genetic screens to enhance insigh...
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Open AccessSARS-CoV-2-associated organs failure and inflammation: a focus on the role of cellular and viral microRNAs
SARS-CoV-2 has been responsible for the recent pandemic all over the world, which has caused many complications. One of the hallmarks of SARS-CoV-2 infection is an induced immune dysregulation, in some cases r...
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Article
Effect of Caffeine Consumption on Cardiovascular Disease: An Updated Review
The incidence of cardiovascular diseases has significantly increased with the expansion of the industrialization of societies, which is notably linked to lifestyle changes and an unhealthy diet. Hence, determi...
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Open AccessA comprehensive review of COVID-19 symptoms and treatments in the setting of autoimmune diseases
After the first reporting of the index case of Severe Acute Respiratory Syndrome (SARS)-CoV-2-associated disease at the end of December 2019, the virus spread quickly throughout the world, prompting the WHO on...
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Open AccessPossible role of HPV/EBV coinfection in anoikis resistance and development in prostate cancer
This study aimed to evaluate the possible role of human papillomavirus (HPV) and Epstein–Barr virus (EBV) coinfection as an etiological factor for prostate cancer (PCa) development.
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The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV
The number of descriptions of emerging viruses has grown at an unprecedented rate since the beginning of the 21st century. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus di...
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Bacteriophages: cancer diagnosis, treatment, and future prospects
Early diagnosis is one of the most important factors in cancer treatment. Unfortunately, despite remarkable advances in the diagnosis and treatment methods of cancers in recent years, these methods are far fro...
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Article
Non-alcoholic fatty liver diseases: from role of gut microbiota to microbial-based therapies
Non-alcoholic fatty liver disease (NAFLD) is the well-known disease of the liver in adults and children throughout the world. The main manifestations related to NAFLD are an unusual storage of lipid in hepatoc...
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Viral infection and atherosclerosis
Several risk factors have been described for the pathogenesis of atherosclerosis. Infectious diseases are suggested to be a causative factor, and some viruses have been studied for their relation with atherosc...
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Open AccessHuman papillomavirus E5 protein, the undercover culprit of tumorigenesis
Human papillomavirus (HPV) is the most common viral infection of the reproductive tract worldwide. It has been well documented that the HPV oncoproteins E6 and E7 play important roles in cancer progression and...
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Effect of equine herpesvirus type 1 (EHV-1) infection of nasal mucosa epithelial cells on integrin alpha 6 and on different components of the basement membrane
The respiratory mucosa is the common port of entry of equine herpesvirus type 1 (EHV-1) and several other alphaherpesviruses. An important prerequisite for successful host invasion of the virus is to cross the...
