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  1. Article

    Open Access

    Ion exchanger in the brain: Quantitative analysis of perineuronally fixed anionic binding sites suggests diffusion barriers with ion sorting properties

    Perineuronal nets (PNs) are a specialized form of brain extracellular matrix, consisting of negatively charged glycosaminoglycans, glycoproteins and proteoglycans in the direct microenvironment of neurons. Sti...

    Markus Morawski, Tilo Reinert, Wolfram Meyer-Klaucke… in Scientific Reports (2015)

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    Article

    Perineuronal Nets Characterized by Vital Labelling, Confocal and Electron Microscopy in Organotypic Slice Cultures of Rat Parietal Cortex and Hippocampus

    Perineuronal nets (PNs) of the extracellular matrix have been shown to develop in organotypic slice cultures largely corresponding with regional patterns known from in vivo experiments. In the present study, we u...

    Gert Brückner, Johannes Kacza, Jens Grosche in Journal of Molecular Histology (2004)

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    Article

    Perineuronal nets show intrinsic patterns of extracellular matrix differentiation in organotypic slice cultures

    Perineuronal nets (PNs), consisting of extracellular matrix proteoglycans, complexed with hyaluronan and colocalized with tenascins, are associated with distinct neuronal populations in mature mammalian brain...

    Gert Brückner, Jens Grosche in Experimental Brain Research (2001)

  4. No Access

    Article

    Developmental patterns of proteoglycan-containing extracellular matrix in perineuronal nets and neuropil of the postnatal rat brain

    The extracellular matrix is involved in various morphogenetic processes which are accompanied by changes in its physicochemical properties and spatial organization. In the adult brain it contributes to cellula...

    Gerlinde Köppe, Gert Brückner, Kurt Brauer, Wolfgang Härtig… in Cell and Tissue Research (1997)

  5. No Access

    Article

    Extracellular matrix organization in various regions of rat brain grey matter

    Previous studies revealed the concentration of extracellular matrix proteoglycans in the so-called perineuronal nets on the one hand and in certain zones of the neuropil on the other. This nonhomogeneous distr...

    Gert Brückner, Wolfgan Härtig, Johannes Kacza, Johannes Seeger… in Journal of Neurocytology (1996)

  6. No Access

    Article

    Digoxigenylated primary antibodies for sensitive dual-peroxidase labelling of neural markers

    This study extends the application of the digoxigenin-anti-digoxigenin (DIG) technique to immunocytochemistry by using digoxigenin-tagged primary antibodies. Certain features of this technique when applied to ...

    Wolfgang Härtig, Gert Brückner, Max Holzer, Kurt Brauer… in Histochemistry and Cell Biology (1995)

  7. No Access

    Article

    Parvalbumin-immunoreactive neurons in the entorhinal cortex of the rat: localization, morphology, connectivity and ultrastructure

    We studied the distribution, morphology, ultrastructure and connectivity of parvalbumin-immunoreactive neurons in the entorhinal cortex of the rat. Immunoreactive cell bodies were found in all layers of the en...

    Floris G. Wouterlood, Wolfgang Härtig, Gert Brückner… in Journal of Neurocytology (1995)

  8. No Access

    Article

    Different levels of acetylcholinesterase and choline acetyltransferase activities in C57Bl/6 and DBA/2 mice are not accompanied with different density of cortical acetylcholinesterase reactive fibers

    Mice of the inbred strains C57Bl/6 and DBA/2 show strain-dependent behavioural differences which have been correlated with variations in the organization of brain cholinergic systems. The aim of our study was ...

    Claudia Schwab, Gert Brückner, Claudio Castellano… in Neurochemical Research (1990)

  9. No Access

    Article

    Histochemistry of glycogen deposition in perinatal rat brain: importance of radial glial cells

    Changes in the glycogen content and patterns of deposition in the develo** rat brain were studied using a light microscopic periodic acid-Schiff method on embryonic days (ED) 14, 16, 18, 20 and postnatal day...

    Gert Brückner, Dietmar Biesold in Journal of Neurocytology (1981)