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  1. Article

    Open Access

    Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

    Axonal degeneration determines the clinical outcome of multiple sclerosis and is thought to result from exposure of denuded axons to immune-mediated damage. Therefore, myelin is widely considered to be a prote...

    Erik Schäffner, Mar Bosch-Queralt, Julia M. Edgar, Maria Lehning in Nature Neuroscience (2023)

  2. Article

    Open Access

    Iron concentrations in neurons and glial cells with estimates on ferritin concentrations

    Brain iron is an essential as well as a toxic redox active element. Physiological levels are not uniform among the different cell types. Besides the availability of quantitative methods, the knowledge about th...

    Anja Reinert, Markus Morawski, Johannes Seeger, Thomas Arendt in BMC Neuroscience (2019)

  3. Article

    Open Access

    Ion exchanger in the brain: Quantitative analysis of perineuronally fixed anionic binding sites suggests diffusion barriers with ion sorting properties

    Perineuronal nets (PNs) are a specialized form of brain extracellular matrix, consisting of negatively charged glycosaminoglycans, glycoproteins and proteoglycans in the direct microenvironment of neurons. Sti...

    Markus Morawski, Tilo Reinert, Wolfram Meyer-Klaucke in Scientific Reports (2015)

  4. No Access

    Article

    Solid State Analysis with the New Leipzig High-Energy Ion Nanoprobe

     The high-energy ion nanoprobe LIPSION at the University of Leipzig has been operational since October 1998. The ultrastable single ended 3.5 MV SINLETRONTM accelerator supplies the H+ or He+ ion beam. A magnetic...

    Jürgen Vogt, Rolf-Horst Flagmeyer, Johannes Heitmann, Dietmar Lehmann in Microchimica Acta (2000)