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Article
Open AccessAssessment of ownership of smart devices and the acceptability of digital health data sharing
Smart portable devices- smartphones and smartwatches- are rapidly being adopted by the general population, which has brought forward an opportunity to use the large volumes of physiological, behavioral, and ac...
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Article
Clinical features and outcomes of patients with diacylglycerol kinase epsilon nephropathy: a nationwide experience
Thrombotic microangiopathy (TMA) is usually caused due to dysregulation of the alternative complement pathway. Rarely, thrombotic microangiopathy is caused by non-complement mediated mutations in diacylglycero...
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Article
Open AccessAssociation of vitamin D status with disease severity and outcome in Indian patients with IgA nephropathy
Vitamin D deficiency has been examined as a risk factor for severity and progression of kidney disease due to its immunomodulatory effects. There is paucity of data about its impact in IgA nephropathy (IgAN).
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Chapter and Conference Paper
ELM-Based Liver Disease Prediction Model
The liver is an important part of the digestive system. Unfortunately, an unhealthy diet affects the liver and it kills more than 2 million people worldwide every year. With so many people affected, it is impo...
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Chapter and Conference Paper
Prediction and Analysis of Liver Disease Using Extreme Learning Machine
Hepar, also known as the liver, is a vital organ of the digestive system which performs hepatic blood flow, helps to clot, etc. Poor eating habits and a sedentary lifestyle, unfortunately, have an impact on th...
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Article
Characterizing predictors of non-diabetic kidney disease (NDKD) in diabetic patients
Diabetic kidney disease (DKD) is the chief cause of renal involvement in diabetic patients. It is primarily a clinical diagnosis. Non-diabetic kidney disease (NDKD) may be missed if they are not biopsied. In t...
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Article
Open AccessACE2 protein expression in lung tissues of severe COVID-19 infection
Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells. The level of ACE2 expression in the lung i...
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Article
Open AccessStructural basis of BAK activation in mitochondrial apoptosis initiation
BCL-2 proteins regulate mitochondrial poration in apoptosis initiation. How the pore-forming BCL-2 Effector BAK is activated remains incompletely understood mechanistically. Here we investigate autoactivation ...
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Chapter and Conference Paper
Detection of Liver Disease Using Machine Learning Techniques: A Systematic Survey
The rapid growth in count of patients suffering from liver disease is a major concern all over the globe. Identification of persons having liver disease is done through liver biopsy and by visual checking of M...
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Article
Therapy and outcomes of C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis
Data on therapy and outcome of dense deposit disease (DDD), C3 glomerulonephritis (C3GN), and immune-complex MPGN (IC-MPGN) in children are limited.
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Article
Low-Grade Fibromyxoid Sarcoma of the External Auditory Canal: A Rare Pathology and Unusual Location
Low-grade fibromyxoid sarcoma (LGFMS) is an enigmatic soft tissue tumor. It frequently presents as a deeply seated mass in the proximal extremities and trunk. Superficial LGFMSs of the head and neck are exceed...
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Article
Open AccessRenal detection of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in malaria associated acute kidney injury: a retrospective case–control study
Acute kidney injury (AKI) is a frequent presentation in malaria infections. Several cases of AKI that are accompanied by clinical symptoms of malaria infection, such as fever, nausea, respiratory distress, and...
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Chapter and Conference Paper
Exploration and Implementation of Classification Algorithms for Patent Classification
Data mining techniques have seen tremendous increase in their usage in the past few years. Patent mining is one of the domains that utilize data mining techniques to a great extent. Patent mining consists of v...
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Chapter and Conference Paper
Exploration and Implementation of Classification Algorithms for Patent Classification
The number of patent documents being filed every year is increasing at a rapid rate which demands for advanced and revolutionized tools to assist in patent mining activities such as Analysis, Detecting Infrin...
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Protocol
Methods to Probe Conformational Activation and Mitochondrial Activity of Proapoptotic BAK
Mitochondrial outer membrane permeabilization (MOMP) is a crucial initiating event in apoptosis that activates the caspase cascade to execute cell demise. The effector B-cell lymphoma 2 (BCL-2) antagonist kill...
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Chapter
Genetic Algorithm Implementation to Optimize the Hybridization of Feature Extraction and Metaheuristic Classifiers
Hybridization represents a promising approach for solving any recognition problem. This chapter presents two face recognition frameworks involving the hybridization of both the feature extraction and classific...
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Article
Pattern of biopsy-proven kidney disease in the elderly in a tertiary care hospital in India: a clinicopathological study
An aging population is an important demographic issue in India. The knowledge base about kidney diseases among the elderly Indians is inadequate. We aim to delineate the clinical profile and spectrum of biopsy...
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Article
Thrombotic microangiopathy and acute kidney injury following vivax malaria
Infection with Plasmodium vivax, a common human parasite, is occasionally recognized to cause severe organ dysfunction similar to P. falciparum infection. Acute kidney injury (AKI) in malaria is...
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Article
Papillary glioneuronal tumor—a rare entity: report of four cases and brief review of literature
Papillary glioneuronal tumors (PGNT) have been recently included as a distinct entity in the WHO classification of tumors of the central nervous system. Their molecular pathogenesis is not clear. In the curren...
