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Article
Severe disease during both primary and secondary dengue virus infections in pediatric populations
Dengue is a global epidemic causing over 100 million cases annually. The clinical symptoms range from mild fever to severe hemorrhage and shock, including some fatalities. The current paradigm is that these se...
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Article
Prediction of human protein interactome of dengue virus non-structural protein 5 (NS5) and its downstream immunological implications
The non-structural protein 5 (NS5) is the most conserved protein among flaviviruses, a family that includes the dengue virus. It functions both as an RNA-dependent RNA polymerase and an RNA-methyltransferase a...
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Article
Open AccessACE2 protein expression in lung tissues of severe COVID-19 infection
Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells. The level of ACE2 expression in the lung i...