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    Article

    Severe disease during both primary and secondary dengue virus infections in pediatric populations

    Dengue is a global epidemic causing over 100 million cases annually. The clinical symptoms range from mild fever to severe hemorrhage and shock, including some fatalities. The current paradigm is that these se...

    Charu Aggarwal, Hasan Ahmed, Pragati Sharma, Elluri Seetharami Reddy in Nature Medicine (2024)

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    Article

    Prediction of human protein interactome of dengue virus non-structural protein 5 (NS5) and its downstream immunological implications

    The non-structural protein 5 (NS5) is the most conserved protein among flaviviruses, a family that includes the dengue virus. It functions both as an RNA-dependent RNA polymerase and an RNA-methyltransferase a...

    Priya Bhatnagar, Prashant Bajpai, Jatin Shrinet, Murali Krishna Kaja in 3 Biotech (2023)

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    Open Access

    ACE2 protein expression in lung tissues of severe COVID-19 infection

    Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells. The level of ACE2 expression in the lung i...

    Atish Gheware, Animesh Ray, Deeksha Rana, Prashant Bajpai in Scientific Reports (2022)