10 Result(s)
within
Friedrich Götz
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessAuthor Correction: Warmth and competence perceptions of key protagonists are associated with containment measures during the COVID-19 pandemic: Evidence from 35 countries
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Article
Open AccessWarmth and competence perceptions of key protagonists are associated with containment measures during the COVID-19 pandemic: Evidence from 35 countries
It is crucial to understand why people comply with measures to contain viruses and their effects during pandemics. We provide evidence from 35 countries (Ntotal = 12,553) from 6 continents during the COVID-19 pan...
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Article
Open AccessThe role of Staphylococcus aureus lipoproteins in hematogenous septic arthritis
Permanent joint dysfunction is a devastating complication in patients with septic arthritis. Staphylococcus aureus (S. aureus) lipoproteins (Lpp), the predominant ligands for TLR2, are known to be arthritogenic a...
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Article
Open AccessMpsAB is important for Staphylococcus aureus virulence and growth at atmospheric CO2 levels
The mechanisms behind carbon dioxide (CO2) dependency in non-autotrophic bacterial isolates are unclear. Here we show that the Staphylococcus aureus mpsAB operon, known to play a role in membrane potential genera...
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Article
Open AccessLugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors
Recently our groups discovered lugdunin, a new cyclic peptide antibiotic that inhibits Staphylococcus aureus epithelial colonization in humans and rodents. In this work, we analyzed its immuno-modulatory and anti...
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Open AccessStaphylococcus aureus induces DNA damage in host cell
Staphylococcus aureus causes serious medical problems in human and animals. Here we show that S. aureus can compromise host genomic integrity as indicated by bacteria-induced histone H2AX phosphorylation, a marke...
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Article
Open AccessLantibiotic production is a burden for the producing staphylococci
Lantibiotics are antimicrobial peptides that contain non-proteinogenic amino acids lanthionine and 3-methyllanthionine and are produced by Gram-positive bacteria. Here we addressed the pros and cons of lantibi...
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Article
Open AccessLipid moieties on lipoproteins of commensal and non-commensal staphylococci induce differential immune responses
Lipoproteins (Lpp) of Gram-positive bacteria are major players in alerting our immune system. Here, we show that the TLR2 response induced by commensal species Staphylococcus aureus and Staphylococcus epidermidis
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Article
Open AccessToll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants
Sepsis caused by Gram-positive bacterial pathogens is a major fatal disease but its molecular basis remains elusive. Toll-like receptor 2 (TLR2) has been implicated in the orchestration of inflammation and sep...
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Article
Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings
The genetic basis for the biosynthesis of large polypeptide antibiotics such as nisin has not been explained so far. We show here that the structural gene epiA encoding the antibiotic epidermin1,2 from Staphyloco...
