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Open AccessLugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors
Recently our groups discovered lugdunin, a new cyclic peptide antibiotic that inhibits Staphylococcus aureus epithelial colonization in humans and rodents. In this work, we analyzed its immuno-modulatory and anti...
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Open AccessTargeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth
Numerous studies have demonstrated that functional mitochondria are required for tumorigenesis, suggesting that mitochondrial oxidative phosphorylation (OXPHOS) might be a potential target for cancer therapy. ...
