7 Result(s)

Article

MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes

The membrane-associated RING-CH (MARCH) proteins are E3 ligases that regulate the stability of various cellular membrane proteins. MARCH8 has been reported to inhibit the infection of HIV-1 and a few other vir...

**aoman Liu, Fengwen Xu, Lili Ren, Fei Zhao, Yu Huang, Liang Wei… in Nature Communications (2021)

Article

Amphotericin B Inhibits Enterovirus 71 Replication by Impeding Viral Entry

Enterovirus 71 (EV71) infection causes hand-foot-and-mouth disease that leads to cardiopulmonary complications and death in young children. There is thus an urgent need to find new treatments to control EV71 i...

Fengwen Xu, **aoxiao Zhao, Siqi Hu, Jian Li, Lijuan Yin, Shan Mei… in Scientific Reports (2016)

Article

BoHV-4 immediate early 1 gene is a dispensable gene and its product is not a bone marrow stromal cell antigen 2 counteracting factor

Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus whose genome was cloned as Bacterial Artificial Chromosome (BAC) and exploited as a gene delivery vector for vaccine purposes. Although BoHV-4 genome has bee...

Valentina Franceschi, Antonio Capocefalo, Sarah Jacca… in BMC Veterinary Research (2015)

Article

The interferon-induced MxB protein inhibits an early step of HIV-1 infection

Zhenlong Liu, Qinghua Pan, Shilei Ding, ** Qian, Fengwen Xu, **ming Zhou… in Retrovirology (2013)

Article

Identification of novel key amino acids at the interface of the transmembrane domains of human BST-2 and HIV-1 Vpu

BST-2 (bone marrow stromal cell antigen 2) is an interferon-inducible protein that inhibits virus release by tethering viral particles to the cell surface. This antiviral activity of BST-2 is antagonized by HI...

**ao**g Pang, Siqi Hu, Jian Li, Fengwen Xu, Shan Mei, **ming Zhou… in Retrovirology (2013)

Article

Tetherin inhibits prototypic foamy virus release

Tetherin (also known as BST-2, CD317, and HM1.24) is an interferon- induced protein that blocks the release of a variety of enveloped viruses, such as retroviruses, filoviruses and herpesviruses. However, the ...

Fengwen Xu, Juan Tan, Ruikang Liu, Dan Xu, Yue Li, Yunqi Geng… in Virology Journal (2011)