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  1. Article

    Open Access

    BoHV-4 immediate early 1 gene is a dispensable gene and its product is not a bone marrow stromal cell antigen 2 counteracting factor

    Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus whose genome was cloned as Bacterial Artificial Chromosome (BAC) and exploited as a gene delivery vector for vaccine purposes. Although BoHV-4 genome has bee...

    Valentina Franceschi, Antonio Capocefalo, Sarah Jacca in BMC Veterinary Research (2015)

  2. Article

    Open Access

    Bovine herpesvirus 4 glycoprotein B is indispensable for lytic replication and irreplaceable by VSVg

    Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus, belonging to Rhadinovirus genus, with no clear association with disease. However, there is increasing evidence of its secondary pathogenic role in cases of ...

    Valentina Franceschi, Antonio Capocefalo, Sandro Cavirani in BMC Veterinary Research (2013)

  3. Article

    Open Access

    Virally and physically transgenized equine adipose-derived stromal cells as a cargo for paracrine secreted factors

    Adipose-Derived Stromal Cells have been shown to have multiple lineage differentiation properties and to be suitable for tissues regeneration in many degenerative processes. Their use has been proposed for the...

    Gaetano Donofrio, Antonio Capocefalo, Valentina Franceschi in BMC Cell Biology (2010)

  4. Article

    Open Access

    Integration of bovine herpesvirus 4 genome into cultured persistently infected host cell genome

    Persistent infection of macrophages with bovine herpesvirus 4 (BoHV-4) has been proposed to play a secondary causal role, along with bacterial infection, in bovine post-partum metritis. Mechanisms of maintenan...

    Gaetano Donofrio, Antonio Capocefalo, Valentina Franceschi in Virology Journal (2010)

  5. Article

    Open Access

    Isolation and characterization of bovine herpesvirus 4 (BoHV-4) from a cow affected by post partum metritis and cloning of the genome as a bacterial artificial chromosome

    Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with a Worldwide distribution in cattle and is often isolated from the uterus of animals with postpartum metritis or pelvic inflammatory disease. Virus strai...

    Gaetano Donofrio, Valentina Franceschi in Reproductive Biology and Endocrinology (2009)

  6. Article

    Open Access

    Bovine endometrial stromal cells display osteogenic properties

    The endometrium is central to mammalian fertility. The endometrial stromal cells are very dynamic, growing and differentiating throughout the estrous cycle and pregnancy. In humans, stromal cells appear to hav...

    Gaetano Donofrio, Valentina Franceschi in Reproductive Biology and Endocrinology (2008)