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Article
Open AccessMARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes
The membrane-associated RING-CH (MARCH) proteins are E3 ligases that regulate the stability of various cellular membrane proteins. MARCH8 has been reported to inhibit the infection of HIV-1 and a few other vir...
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Article
Open AccessTwo-Dimensional Black Phosphorus Nanomaterials: Emerging Advances in Electrochemical Energy Storage Science
Two-dimensional black phosphorus (2D BP) possesses huge potential in electrochemical energy storage field owing to its unique electronic structure, high ch...
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Article
Open AccessBreaking translational symmetry via polymer chain overcrowding in molecular bottlebrush crystallization
One of the fundamental laws in crystallization is translational symmetry, which accounts for the profound shapes observed in natural mineral crystals and snowflakes. Herein, we report on the spontaneous format...
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Article
Open AccessBlock copolymer crystalsomes with an ultrathin shell to extend blood circulation time
In water, amphiphilic block copolymers (BCPs) can self-assemble into various micelle structures depicting curved liquid/liquid interface. Crystallization, which is incommensurate with this curved space, often ...
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Chapter and Conference Paper
Irregular Spatial Cluster Detection Based on H1N1 Flu Simulation in Bei**g
Spatial cluster detection of infected areas is widely used for disease surveillance, prevention and containment. However, the commonly used cluster methods cannot resolve the conflicts between the accuracy and...
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Article
Open AccessAmphotericin B Inhibits Enterovirus 71 Replication by Impeding Viral Entry
Enterovirus 71 (EV71) infection causes hand-foot-and-mouth disease that leads to cardiopulmonary complications and death in young children. There is thus an urgent need to find new treatments to control EV71 i...
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Article
Open AccessHighly robust crystalsome via directed polymer crystallization at curved liquid/liquid interface
Lipids and amphiphilic block copolymers spontaneously self-assemble in water to form a plethora of micelles and vesicles. They are typically fluidic in nature and often mechanically weak for applications such ...
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Article
Open AccessIdentification of novel key amino acids at the interface of the transmembrane domains of human BST-2 and HIV-1 Vpu
BST-2 (bone marrow stromal cell antigen 2) is an interferon-inducible protein that inhibits virus release by tethering viral particles to the cell surface. This antiviral activity of BST-2 is antagonized by HI...
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Article
Open AccessIncreasing risk behaviour can outweigh the benefits of antiretroviral drug treatment on the HIV incidence among men-having-sex-with-men in Amsterdam
The transmission through contacts among MSM (men who have sex with men) is one of the dominating contributors to HIV prevalence in industrialized countries. In Amsterdam, the capital of the Netherlands, the MS...
