17 Result(s)

Article

Application of a Ball Milling Technique for the Condensation of Anthranilic Hydrazides with Aromatic Aldehydes Towards 4-Quinazolinone Derivatives*

An environmentally friendly method was applied to prepare anthranilic hydrazones and quinazolin-4(1H)-ones from anthranilic hydrazides and a number of aldehydes in solventless medium. The condensations proceed...

T. Magyar, F. Miklós, L. Lázár, F. Fülöp in Chemistry of Heterocyclic Compounds (2015)

Article

Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies

Parkinson’s, Alzheimer’s and Huntington’s diseases are chronic neurodegenerative disorders of a progressive nature which lead to a considerable deterioration of the quality of life. Their pathomechanisms displ...

D. Zádori, P. Klivényi, E. Vámos, F. Fülöp, J. Toldi… in Journal of Neural Transmission (2009)

Article

HPLC Enantioseparation of 1-(α-Aminobenzyl)-2-naphthol and 2-(α-Aminobenzyl)-1-naphthol Analogs on a β-Cyclodextrin-Based Chiral Stationary Phase

The enantiomers of 1-(α-aminobenzyl)-2-naphthol and 2-(α-aminobenzyl)-1-naphthol analogs were separated isothermally on a 3,5-dimethylphenylcarbamoylated β-cyclodextrin-based chiral stationary phase (Cyclobond DM...

R. Berkecz, I. Ilisz, A. Ivanov-Sztojkov, I. Szatmári, F. Fülöp… in Chromatographia (2007)

Article

Comparison of Separation Efficiency of Macrocyclic Glycopeptide-Based Chiral Stationary Phases for the LC Enantioseparation of β-Amino Acids

Direct reversed-phase high-performance liquid chromatographic methods were developed for the separation of enantiomers of eighteen unnatural β-amino acids, including several β-3-homo-amino acids. The direct separ...

A. Sztojkov-Ivanov, L. Lázár, F. Fülöp, D. W. Armstrong, A. Péter in Chromatographia (2006)

Article

LC Enantioseparation of β-Lactam and β-Amino Acid Stereoisomers and a Comparison of Macrocyclic Glycopeptide- and β-Cyclodextrin-Based Columns

Direct reversed-phase high-performance liquid chromatographic methods were developed for the separation of the enantiomers of tricyclic β-lactams, cis-3,4-benzo-6-azabicyclo[3.2.0]heptan-7-one, cis-4,5-benzo-7-az...

R. Berkecz, R. Török, I. Ilisz, E. Forró, F. Fülöp, D. W. Armstrong… in Chromatographia (2006)

Article

LC Enantioseparation of Aryl-Substituted β-Lactams Using Variable-Temperature Conditions

Direct reversed-phase high-performance liquid chromatographic methods were developed for the separation of enantiomers of β-lactams. The enantiomers of 7 aryl-substituted β-lactams were separated on chiral statio...

R. Berkecz, I. Ilisz, E. Forró, F. Fülöp, D. W. Armstrong, A. Péter in Chromatographia (2006)

Article

High-Performance Liquid Chromatographic Separation of Stereoisomers of β-Amino Acids and a Comparison of Separation Efficiencies on Chirobiotic T and TAG Columns

Direct and indirect reversed-phase high-performance liquid chromatographic methods were developed for the separation of enantiomers of seventeen unnatural β-amino acids, including several β-3-homo amino acids....

A. Árki, D. Tourwé, M. Solymár, F. Fülöp, D. W. Armstrong, A. Péter in Chromatographia (2004)

Article

Comparison of isothiocyanate chiral derivatizing reagents for high-performance liquid chromatography

This paper describes the synthesis of a new chiral derivatizing reagent, (1S, 2R)-1-acetoxy-1-phenyl-2-propyl isothiocyanate ((S,R)-APPI), which is readily available in both enantiomeric forms after a straightfor...

M. Péter, F. Fülöp in Chromatographia (2002)

Chapter

Synthesis and pharmacological properties of oxytocin antagonists containing conformationally constrained amino acids

G. K. Tóth, K. Bakos, I. Zupkóo, F. FüLöP, I. Pávó… in Peptide Science — Present and Future (2002)

Article

High-performance liquid chromatographic separation of unusual amino acid enantiomers derivatized with (1S,2S)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propyl-isothiocyanate

A new chiral derivatizing agent (CDA), (1S,2S)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propylisothiocyanate, (S,S)-DANI, was applied to the separation of the enantiomers of unusual amino acids containing two chiral cen...

A. Péter, M. Péter, F. Fülöp, G. Török, G. Tóth, D. Tourwé, J. Sápi in Chromatographia (2000)

Article

Development of new isothiocyanate-based chiral derivatizing agent for amino acids

(1S,2S)-1,3-Diacetoxy-1-(4-nitrophenyl)-2-propylisothiocyanate [(S,S)-DANI] has been developed as a new chiral derivatizing agent for resolution of compounds containing an amino group. The reagent is readily avai...

M. Peter, A. Peter, F. Fülöp in Chromatographia (1999)

Article

High-Performance liquid chromatographic separation of enantiomers of unusual amino acids possessing cycloalkane or cycloalkene skeletons on a chiral crown ether containing stationary phase

Direct reversed-phase high-performance liquid chromatographic methods were developed for the separation and identification of the enantiomers of mono- and bicyclic racemic β-amino acids:cis- andtrans-2-aminocyclo...

G. Török, A. Péter, F. Fülöp in Chromatographia (1998)

Article

An operated case of Holt-Oram syndrome with autosomal dominant inheritance

This report is concerned with a patient successfully operated forHolt-Oram syndrome. The disorder is inherited dominantly with complete penetrance and variable expressivity. It is pointed out that in cases of con...

Z. Czakó, A. Gömöry, P. Homolay, S. Bacsa, S. Kiss… in Basic Research in Cardiology (1976)