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  1. Article

    Open Access

    In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin

    The multidrug resistance (MDR) proteins are present in a majority of human tumours. Their activity is important to understand the chemotherapeutic failure. A search for MDR-reversing compounds was conducted am...

    N Gyémánt, H Engi, Z Schelz, I Szatmári, D Tóth, F Fülöp… in British Journal of Cancer (2010)

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  2. Article

    The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations

    The rs1990760 polymorphism (Ala946Thr) of interferon induced with helicase C domain 1 (IFIH1) has been proposed to associate with type 1 diabetes. In this study, association between IFIH1 Ala946Thr and type 1 dia...

    A. Jermendy, I. Szatmári, A. P. Laine, K. Lukács, K. H. Horváth, A. Körner… in Diabetologia (2010)

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  3. No Access

    Article

    HPLC Enantioseparation of 1-(α-Aminobenzyl)-2-naphthol and 2-(α-Aminobenzyl)-1-naphthol Analogs on a β-Cyclodextrin-Based Chiral Stationary Phase

    The enantiomers of 1-(α-aminobenzyl)-2-naphthol and 2-(α-aminobenzyl)-1-naphthol analogs were separated isothermally on a 3,5-dimethylphenylcarbamoylated β-cyclodextrin-based chiral stationary phase (Cyclobond DM...

    R. Berkecz, I. Ilisz, A. Ivanov-Sztojkov, I. Szatmári, F. Fülöp… in Chromatographia (2007)

  4. No Access

    Chapter and Conference Paper

    The Effect of Beta-Cyclodextrin Complexation on Plasma Levels of Ipriflavone and its Main Metabolites

    Ipriflavone or its beta-cyclodextrin complex were administered orally in suspension to rats. In another experiment ipriflavone tablets (200 mg) or ipriflavone-beta-cyclodextrin complex tablets (equivalent to 2...

    F. Lévai, K. Tóth, I. Szatmári, Z. Vargay in Proceedings of the Fourth International Sy… (1988)

  5. No Access

    Chapter and Conference Paper

    The Comparison of Absorption, Distribution and Elimination of Ipriplavone-14C and Ipriplavone-14C-Beta-Cyclodextrin Inclusion Complex

    Ipriflavone-14C and ipriflavone-14C-beta-cyclo-dextrin complex were administered orally to male and female Wistar rats. The bioavailability showed to be significantly enhanced by CD-complexation. There were no...

    F. Lévai, I. Szatmári, Z. Vargay in Proceedings of the Fourth International Sy… (1988)

  6. No Access

    Chapter and Conference Paper

    Pharmacokinetics of Dimethyl-Beta-Cyclodextrin in Rats

    The blood levels, organ levels and elimination of dimethyl-beta-cyclodextrin were studied in Wistar rats after oral and intravenous administration of C-14 labelled compound. The absorption of DIMEB is very poo...

    I. Szatmári… in Proceedings of the Fourth International Symposium on Cyclodextrins (1988)

  7. No Access

    Article

    The fate of Drotaverine — Acephyllinate+ in rat and man I. Absorption, distribution and excretion in the rat

    Two different labelled forms were used for the pharmacokinetic investigations: the carbon 1 in the isoquinoline ring (Drotaverine-14C-Acephyllinate) and the carboxyl group of theophylline-7-acetic acid (Drotaveri...

    I. Szatmári, G. Simon, Z. Vargay, É. Tóth… in European Journal of Drug Metabolism and Ph… (1984)

  8. No Access

    Article

    The fate of Drotaverine-Acephyllinate in rat and man II. Human pharmacokinetics of Drotaverine-14C-Acephyllinate

    Pharmacokinetics of Drotaverine-Acephyllinate, Chinoin was investigated in seven male volunteers using14C labelled drug. Drotaverine-Acephyllinate was administered at a 100 mg single oral dose. Measurements of to...

    Z. Vargay, T. Deutsch, I. Szatmári, T. SzÜts… in European Journal of Drug Metabolism and Ph… (1984)