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The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction

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  1. Article

    Open Access

    Global variations in funding and use of hemodialysis accesses: an international report using the ISN Global Kidney Health Atlas

    There is a lack of contemporary data describing global variations in vascular access for hemodialysis (HD). We used the third iteration of the International Society of Nephrology Global Kidney Health Atlas (IS...

    Anukul Ghimire, Samveg Shah, Utkarsh Chauhan, Kwaifa Salihu Ibrahim in BMC Nephrology (2024)

  2. Article

    Open Access

    A secondary analysis of concurrent use of metformin and tolvaptan in ADPKD tolvaptan trials

    I. Kitty Stanley, Anton M. Palma, Andrea K. Viecelli in Journal of Nephrology (2024)

  3. Article

    Open Access

    Training healthcare professionals to administer Goal Attainment Scaling as an outcome measure

    Goals generated by Goal Attainment Scaling (GAS) can be used as an outcome measure to promote person-centred research and care. There are no training packages which support its use outside of the rehabilitatio...

    Benignus Logan, Andrea K. Viecelli in Journal of Patient-Reported Outcomes (2024)

  4. Article

    Open Access

    Multi-center, pragmatic, cluster-randomized, controlled trial of standardized peritoneal dialysis (PD) training versus usual care on PD-related infections (the TEACH-PD trial): trial protocol

    Peritoneal dialysis (PD)-related infections, such as peritonitis, exit site, and tunnel infections, substantially impair the sustainability of PD. Accordingly, PD-related infection is the top-priority research...

    Josephine S. F. Chow, Neil Boudville, Yeoungjee Cho, Suetonia Palmer in Trials (2023)

  5. Article

    Clinical features, management and outcomes of peritoneal dialysis patients during Delta and Omicron waves of COVID-19 infections

    There were discrete outbreaks of SARS-CoV-2 infection in 2021 (Delta wave) and 2022 (Omicron wave) in Singapore, which affected patients receiving peritoneal dialysis (PD).

    Htay Htay, Marjorie Wai Yin Foo, Mathini Jayaballa in International Urology and Nephrology (2023)

  6. Article

    Open Access

    Uptake of pediatric patient-reported outcome and experience measures and challenges associated with their implementation in Alberta: a mixed-methods study

    Implementing Patient-reported Outcome Measures (PROMs) and Patient-reported Experience Measures (PREMs) is an effective way to deliver patient- and family-centered care (PFCC). Although Alberta Health Services...

    Sumedh Bele, Sarah Rabi, Muning Zhang, Sadia Ahmed in BMC Pediatrics (2023)

  7. Article

    Open Access

    Health care impact of implementing a clinical pathway for acute care of pediatric concussion: a stepped wedge, cluster randomised trial

    To test the effects of actively implementing a clinical pathway for acute care of pediatric concussion on health care utilization and costs.

    Keith Owen Yeates, Karen M. Barlow, Bruce Wright in Canadian Journal of Emergency Medicine (2023)

  8. Article

    Open Access

    The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT (NASCENT) program: protocol for a stepped wedge cluster randomized trial of a hospital-level Neonatal Abstinence Syndrome rooming-in intervention

    Neonatal Abstinence Syndrome (NAS), a problem common in newborns exposed to substances in-utero, is an emerging health concern. In traditional models of care, infants with NAS are routinely separated from thei...

    Osnat Wine, Deborah McNeil, Seija K. Kromm, Karen Foss in BMC Health Services Research (2023)

  9. Article

    Baseline characteristics of participants in the NAVKIDS2 trial: a patient navigator program in children with chronic kidney disease

    Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to over...

    Chandana Guha, Rabia Khalid, Anita van Zwieten, Anna Francis in Pediatric Nephrology (2023)

  10. Article

    Open Access

    PREBIOTIC: a study protocol of a randomised controlled trial to assess prebiotic supplementation in kidney transplant recipients for preventing infections and gastrointestinal upset — a feasibility study

    Modulating the microbiota in the large intestine of kidney transplant recipients through prebiotic supplementation may prevent infectious complications from occurring. To date, there have been no interventiona...

    Samuel Chan, Carmel M. Hawley, Elaine M. Pascoe in Pilot and Feasibility Studies (2023)

  11. Article

    Epidemiology of peritoneal dialysis outcomes

    Peritoneal dialysis (PD) is an important home-based treatment for kidney failure and accounts for 11% of all dialysis and 9% of all kidney replacement therapy globally. Although PD is available in 81% of count...

    Aminu K. Bello, Ikechi G. Okpechi, Mohamed A. Osman in Nature Reviews Nephrology (2022)

  12. Article

    Open Access

    Study protocol for Vascular Access outcome measure for function: a vaLidation study In hemoDialysis (VALID)

    A functioning vascular access (VA) is crucial to providing adequate hemodialysis (HD) and considered a critically important outcome by patients and healthcare professionals. A validated, patient-important outc...

    Andrea K. Viecelli, Armando Teixeira-Pinto, Andrea Valks, Richard Baer in BMC Nephrology (2022)

  13. Article

    Open Access

    NAVKIDS2 trial: a multi-centre, waitlisted randomised controlled trial of a patient navigator intervention in children with chronic kidney disease — statistical analysis plan and update to the protocol

    This update summarises key changes made to the protocol since the publication of the original protocol for the NAVKIDS2 trial of patient navigators for children with chronic kidney disease (CKD) experiencing soci...

    Anita van Zwieten, Elizabeth G. Ryan, Patrina Caldwell, Kirsten Howard in Trials (2022)

  14. Article

    Open Access

    Patient-reported outcome measures in pediatric asthma care: using theoretical domains framework to explore healthcare providers’ perceptions

    Patient-reported outcome measures (PROMs) play an important role in promoting and supporting patient and family-centered care. Implementing interventions like PROMs in routine clinical care require key stakeho...

    Sumedh Bele, Sarah Rabi, Muning Zhang in Journal of Patient-Reported Outcomes (2022)

  15. Article

    Epidemiology of haemodialysis outcomes

    Haemodialysis (HD) is the commonest form of kidney replacement therapy in the world, accounting for approximately 69% of all kidney replacement therapy and 89% of all dialysis. Over the last six decades since ...

    Aminu K. Bello, Ikechi G. Okpechi, Mohamed A. Osman in Nature Reviews Nephrology (2022)

  16. Article

    Open Access

    Immunosuppression therapy for idiopathic membranous nephropathy: systematic review with network meta-analysis

    Idiopathic membranous nephropathy is a common cause of nephrotic syndrome in adults. The Kidney Disease Improving Global Outcomes guidelines recommend rituximab or cyclophosphamide and steroids, or calcineurin...

    Bhadran Bose, Edmund Y. M. Chung, Regina Hong in Journal of Nephrology (2022)

  17. Article

    Educating primary healthcare providers about kidney disease

    Chronic kidney disease is a major public health problem that is associated with excessive morbidity, mortality and healthcare costs. However, limited clinician awareness of chronic kidney disease is universall...

    Aminu K. Bello, David W. Johnson in Nature Reviews Nephrology (2022)

  18. Article

    Open Access

    Correction to: Statistical analysis plan for better evidence for selecting transplant fluids (BEST-fluids): a randomised controlled trial of the effect of intravenous fluid therapy with balanced crystalloid versus saline on the incidence of delayed graft function in deceased donor kidney transplantation

    Elaine M. Pascoe, Steven J. Chadban, Magid A. Fahim, Carmel M. Hawley in Trials (2022)

  19. Article

    Open Access

    Statistical analysis plan for Better Evidence for Selecting Transplant Fluids (BEST-Fluids): a randomised controlled trial of the effect of intravenous fluid therapy with balanced crystalloid versus saline on the incidence of delayed graft function in deceased donor kidney transplantation

    Delayed graft function, or the requirement for dialysis due to poor kidney function, is a frequent complication of deceased donor kidney transplantation that is associated with inferior outcomes. Intravenous f...

    Elaine M. Pascoe, Steven J. Chadban, Magid A. Fahim, Carmel M. Hawley in Trials (2022)

  20. Article

    Open Access

    Translating Emergency Knowledge for Kids (TREKK): using research evidence to improve outcomes for children and families in emergency departments across Canada

    Lisa Knisley, Lisa Hartling, Mona Jabbour in Canadian Journal of Emergency Medicine (2022)

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