35 Result(s)

Article

Revised cardiac risk index in predicting cardiovascular complications in patients receiving chronic kidney replacement therapy undergoing elective general surgery

The Revised Cardiac Risk Index (RCRI) is a six-parameter model that is commonly used in assessing individual 30-day perioperative cardiovascular risk before general surgery, but its use in patients on chronic ...

Dharmenaan Palamuthusingam, Elaine M. Pascoe, Carmel M. Hawley… in Perioperative Medicine (2024)

Article

A secondary analysis of concurrent use of metformin and tolvaptan in ADPKD tolvaptan trials

I. Kitty Stanley, Anton M. Palma, Andrea K. Viecelli… in Journal of Nephrology (2024)

Article

Multi-center, pragmatic, cluster-randomized, controlled trial of standardized peritoneal dialysis (PD) training versus usual care on PD-related infections (the TEACH-PD trial): trial protocol

Peritoneal dialysis (PD)-related infections, such as peritonitis, exit site, and tunnel infections, substantially impair the sustainability of PD. Accordingly, PD-related infection is the top-priority research...

Josephine S. F. Chow, Neil Boudville, Yeoungjee Cho, Suetonia Palmer… in Trials (2023)

Article

Baseline characteristics of participants in the NAVKIDS² trial: a patient navigator program in children with chronic kidney disease

Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to over...

Chandana Guha, Rabia Khalid, Anita van Zwieten, Anna Francis… in Pediatric Nephrology (2023)

Article

PREBIOTIC: a study protocol of a randomised controlled trial to assess prebiotic supplementation in kidney transplant recipients for preventing infections and gastrointestinal upset — a feasibility study

Modulating the microbiota in the large intestine of kidney transplant recipients through prebiotic supplementation may prevent infectious complications from occurring. To date, there have been no interventiona...

Samuel Chan, Carmel M. Hawley, Elaine M. Pascoe… in Pilot and Feasibility Studies (2023)

Article

Approaches to prioritising research for clinical trial networks: a sco** review

Prioritisation of clinical trials ensures that the research conducted meets the needs of stakeholders, makes the best use of resources and avoids duplication. The aim of this review was to identify and critica...

Rachael L. Morton, Haitham Tuffaha, Vendula Blaya-Novakova, Jenean Spencer… in Trials (2022)

Article

Study protocol for Vascular Access outcome measure for function: a vaLidation study In hemoDialysis (VALID)

A functioning vascular access (VA) is crucial to providing adequate hemodialysis (HD) and considered a critically important outcome by patients and healthcare professionals. A validated, patient-important outc...

Andrea K. Viecelli, Armando Teixeira-Pinto, Andrea Valks, Richard Baer… in BMC Nephrology (2022)

Article

NAVKIDS² trial: a multi-centre, waitlisted randomised controlled trial of a patient navigator intervention in children with chronic kidney disease — statistical analysis plan and update to the protocol

This update summarises key changes made to the protocol since the publication of the original protocol for the NAVKIDS² trial of patient navigators for children with chronic kidney disease (CKD) experiencing soci...

Anita van Zwieten, Elizabeth G. Ryan, Patrina Caldwell, Kirsten Howard… in Trials (2022)

Article

Correction to: Statistical analysis plan for better evidence for selecting transplant fluids (BEST-fluids): a randomised controlled trial of the effect of intravenous fluid therapy with balanced crystalloid versus saline on the incidence of delayed graft function in deceased donor kidney transplantation

Elaine M. Pascoe, Steven J. Chadban, Magid A. Fahim, Carmel M. Hawley… in Trials (2022)

Article

Activities supporting the growth of Clinical Trial Networks in Australia

Clinical Trial Networks in which trialists work collaboratively enable multi-site, large-scale, high-quality clinical trials to be efficiently run. Although the benefits of Clinical Trial Networks are largely ...

Fiona Nemeh, Rachelle Buchbinder, Carmel M. Hawley, Mark R. Nelson… in Trials (2022)

Article

Statistical analysis plan for Better Evidence for Selecting Transplant Fluids (BEST-Fluids): a randomised controlled trial of the effect of intravenous fluid therapy with balanced crystalloid versus saline on the incidence of delayed graft function in deceased donor kidney transplantation

Delayed graft function, or the requirement for dialysis due to poor kidney function, is a frequent complication of deceased donor kidney transplantation that is associated with inferior outcomes. Intravenous f...

Elaine M. Pascoe, Steven J. Chadban, Magid A. Fahim, Carmel M. Hawley… in Trials (2022)

Article

Conducting clinical trials during the COVID-19 pandemic—a collaborative trial network response

The unprecedented demand placed on healthcare systems from the COVID-19 pandemic has forced a reassessment of clinical trial conduct and feasibility. Consequently, the Australasian Kidney Trials Network (AKTN)...

Laura Robison, Yeoungjee Cho, Andrea K. Viecelli, David W. Johnson… in Trials (2021)

Article

Study Protocol for Better Evidence for Selecting Transplant Fluids (BEST-Fluids): a pragmatic, registry-based, multi-center, double-blind, randomized controlled trial evaluating the effect of intravenous fluid therapy with Plasma-Lyte 148 versus 0.9% saline on delayed graft function in deceased donor kidney transplantation

Delayed graft function, the requirement for dialysis due to poor kidney function post-transplant, is a frequent complication of deceased donor kidney transplantation and is associated with inferior outcomes an...

Michael G. Collins, Magid A. Fahim, Elaine M. Pascoe, Kathryn B. Dansie… in Trials (2020)

Article

Effect of extended hours dialysis on markers of chronic kidney disease-mineral and bone disorder in the ACTIVE Dialysis study

Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD) is a significant cause of morbidity among haemodialysis patients and is associated with pathological changes in phosphate, calcium and parathyroid h...

Zhipeng Zhan, Brendan Smyth, Nigel D. Toussaint, Nicholas A. Gray, Li Zuo… in BMC Nephrology (2019)

Article

Progression of arterial stiffness is associated with changes in bone mineral markers in advanced CKD

Arterial stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with chronic kidney disease (CKD). There are limited prospective data however on progression of arterial stiffn...

Rathika Krishnasamy, Sven-Jean Tan, Carmel M. Hawley, David W. Johnson… in BMC Nephrology (2017)

Article

Standardised outcomes in nephrology – Haemodialysis (SONG-HD): study protocol for establishing a core outcome set in haemodialysis

Chronic kidney disease is a significant contributor to mortality and morbidity worldwide, and the number of people who require dialysis or transplantation continues to increase. People on dialysis are 15 times...

Allison Tong, Braden Manns, Brenda Hemmelgarn, David C. Wheeler, Peter Tugwell… in Trials (2015)

Article

Association between serum alkaline phosphatase and primary resistance to erythropoiesis stimulating agents in chronic kidney disease: a secondary analysis of the HERO trial

Erythropoiesis stimulating agent (ESA)-resistant anemia is common in chronic kidney disease (CKD).

Sunil V. Badve, Lei Zhang, Jeff S. Coombes… in Canadian Journal of Kidney Health and Dise… (2015)

Article

Left ventricular global longitudinal strain is associated with cardiovascular risk factors and arterial stiffness in chronic kidney disease

Global longitudinal strain (GLS) has emerged as a superior method for detecting left ventricular (LV) systolic dysfunction compared to ejection fraction (EF) on the basis that it is less operator dependent and...

Rathika Krishnasamy, Carmel M. Hawley, Tony Stanton, Elaine M. Pascoe… in BMC Nephrology (2015)

Article

A randomized trial of sodium-restriction on kidney function, fluid volume and adipokines in CKD patients

Dietary sodium restriction is a key management strategy in chronic kidney disease (CKD). Recent evidence has demonstrated short-term reduction in blood pressure (BP) and proteinuria with sodium restriction, ho...

Katrina L Campbell, David W Johnson, Judith D Bauer, Carmel M Hawley… in BMC Nephrology (2014)

Article

Dialysate interleukin-6 predicts increasing peritoneal solute transport rate in incident peritoneal dialysis patients

Repeated exposure to peritoneal dialysis (PD) solutions contributes to cumulative intraperitoneal inflammation and peritoneal injury. The present study aimed to explore the capacity of dialysate interleukin-6(...

Yeoungjee Cho, David W Johnson, David A Vesey, Carmel M Hawley… in BMC Nephrology (2014)