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Article
Open AccessPREBIOTIC: a study protocol of a randomised controlled trial to assess prebiotic supplementation in kidney transplant recipients for preventing infections and gastrointestinal upset — a feasibility study
Modulating the microbiota in the large intestine of kidney transplant recipients through prebiotic supplementation may prevent infectious complications from occurring. To date, there have been no interventiona...
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Article
Open AccessRetrospective analysis of real-world treatment patterns and clinical outcomes in patients with advanced non-small cell lung cancer starting first-line systemic therapy in the United Kingdom
The treatment landscape for advanced non-small cell lung cancer (aNSCLC) has evolved rapidly since immuno-oncology (IO) therapies were introduced. This study used recent data to assess real-world treatment pat...
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Article
Open AccessInsights on autophagosome–lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5
Pivotal to the maintenance of cellular homeostasis, macroautophagy (hereafter autophagy) is an evolutionarily conserved degradation system that involves sequestration of cytoplasmic material into the double-me...
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Article
Open AccessBMI and its association with death and the initiation of renal replacement therapy (RRT) in a cohort of patients with chronic kidney disease (CKD)
A survival advantage associated with obesity has often been described in dialysis patients. The association of higher body mass index (BMI) with mortality and renal replacement therapy (RRT) in preterminal chr...
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Article
Open AccessBody mass index in an Australian population with chronic kidney disease
Obesity emerged as the leading global health concern in 2017. Although higher body mass index (BMI) is a health risk in the general population, its implications for chronic kidney disease (CKD) are not entirel...
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Article
Computational fluid dynamics studies on the effectiveness of sidewall sprinklers to suppress the fire at the undercarriage of mass rapid transit train
This paper reports the computational fluid dynamics (CFD) studies of sidewall automatic fire sprinklers installed adjacent to and in close proximity to the trains to suppress the fire at the undercarriage of t...
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Article
Open AccessAn association between membranoproliferative glomerulonephritis and metastatic colorectal carcinoma: a case report
Membranoproliferative glomerulonephritis is a common pattern of glomerular injury in monoclonal gammopathy, but has only rarely been associated with solid organ tumors, mainly lung, renal, gastric, breast, and...
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Article
An Unusual Case of Pancreatic Cancer with Leptomeningeal Infiltration
Pancreatic cancer is a common malignancy and often presents at an advanced stage. Metastases are common but neurological involvement is rare. We aim to describe an unusual case of leptomeningeal involvement fr...
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Syndrome X and the Benefits of Weight Loss
Obesity is the most common metabolic disorder in the Western world. Defined by a body mass index (BMI) equal to or greater than 30, it affects an estimated 33% of Americans, including more than 58 million adul...
