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  1. Article

    Open Access

    Application of Design of Experiment in the Optimization of Apixaban-Loaded Solid Lipid Nanoparticles: In Vitro and In Vivo Evaluation

    Solid lipid nanoparticles (SLnPs) are usually utilized as lipid-based formulations for enhancing oral bioavailability of BCS class IV drugs. Accordingly, the objective of this work was to investigate the effec...

    Safaa E. Ramadan, Sanaa A. El-Gizawy, Mohamed A. Osman, Mona F. Arafa in AAPS PharmSciTech (2023)

  2. Article

    Open Access

    Lithium Sorption/Desorption in Some Alkaline Soils: Modeling of the Kinetics Behavior

    Global concern over lithium (Li) in the environment has significantly increased due to its widespread uses. However, the literature review on Li kinetics in alkaline soils is scant. Hence, batch experiments we...

    Tamer A. Elbana, Mohamed A. Osman in Water, Air, & Soil Pollution (2023)

  3. Article

    Epidemiology of peritoneal dialysis outcomes

    Peritoneal dialysis (PD) is an important home-based treatment for kidney failure and accounts for 11% of all dialysis and 9% of all kidney replacement therapy globally. Although PD is available in 81% of count...

    Aminu K. Bello, Ikechi G. Okpechi, Mohamed A. Osman in Nature Reviews Nephrology (2022)

  4. Article

    Epidemiology of haemodialysis outcomes

    Haemodialysis (HD) is the commonest form of kidney replacement therapy in the world, accounting for approximately 69% of all kidney replacement therapy and 89% of all dialysis. Over the last six decades since ...

    Aminu K. Bello, Ikechi G. Okpechi, Mohamed A. Osman in Nature Reviews Nephrology (2022)

  5. No Access

    Article

    Investigation of the effect of verapamil on the regional absorption of sofosbuvir from rabbit intestine in situ

    Sofosbuvir, a nucleotide antiviral drug, is a Biopharmaceutics Classification System (BCS) class III prodrug suffering from limited intestinal absorption due to its high hydrophilicity and low intestinal perme...

    Nada M. Mohsen, Esmat E. Zein El-Din in DARU Journal of Pharmaceutical Sciences (2022)

  6. No Access

    Article

    Influential role of CdS film thickness in improving CdS/CdTe junction performance for solar cells: structural, optical, and electrical characterizations

    CdS films of different thicknesses (d ≈ 100–300 nm) are deposited on the glass substrate by thermal evaporation technique. The structure of these films had been studied by Rietveld refinement and atomic pressure ...

    Essam R. Shaaban, Mohamed A. Osman in Journal of Materials Science: Materials in… (2022)

  7. Article

    Open Access

    The melittology research in Northern Africa and the Middle East: past and present situations

    More than 20,000 species in the superfamily Apoidea have been identified worldwide. This superfamily includes the most important group of insect pollinators that contribute to the integrity of ecosystems.

    Mohamed A. Shebl, Faten Ben Abdelkader in The Journal of Basic and Applied Zoology (2021)

  8. No Access

    Article

    Effect of zinc oxide nanoparticles on broilers’ performance and health status

    The current study investigated the effects of zinc oxide nanoparticles (ZONPs) and oxytetracycline (OTC) supplementation on broilers’ behavior, performance, carcass quality, biochemical parameters, and intesti...

    Usama T. Mahmoud, Hosnia S. Abdel-Mohsein in Tropical Animal Health and Production (2020)

  9. No Access

    Article

    Determination of neuroinflammatory biomarkers in autistic and neurotypical Saudi children

    To identify neuroinflammatory biomarkers in patients with various severity of autism spectrum disorder (ASD) increases the insight about the pathogenesis and pathophysiology of this neurodevelopmental disorder...

    Najat O. Hamed, Laila-Al-Ayadhi, Mohamed A. Osman in Metabolic Brain Disease (2019)

  10. Article

    Open Access

    Enhanced cutaneous wound healing in rats following topical delivery of insulin-loaded nanoparticles embedded in poly(vinyl alcohol)-borate hydrogels

    Insulin plays an important role in the wound healing process, but its method of delivery to the wound bed and subsequent effect on rate of healing is less well investigated. In this study, we evaluated the the...

    Dalia H. Abdelkader, Murtaza M Tambuwala in Drug Delivery and Translational Research (2018)

  11. No Access

    Article

    Enhancement of Dissolution Rate and Intestinal Stability of Clopidogrel Hydrogen Sulfate

    Clopidogrel is an antiplatelet and antithrombotic prodrug. It has poor oral bioavailability due to poor dissolution and possible premature degradation in the intestine. Accordingly, the objective of this study...

    Dina E. Bali, Mohamed A. Osman in European Journal of Drug Metabolism and Ph… (2016)

  12. No Access

    Chapter

    Thermal Properties of Carbon Nanotubes

    The experimental observation of carbon nanotubes by Sumio Iijima in 1991 [1], sparked a significant effort in theoretical and experimental investigation of carbon nanotubes and related structures. The studies ...

    Mohamed. A. Osman, Aron W. Cummings in Molecular Building Blocks for Nanotechnolo… (2007)

  13. No Access

    Chapter

    Sub-Picosecond Luminescence Spectra of Photoexcited Electrons Relaxation in p-GaAs

    Femtosecond lasers have allowed closer examination of the dynamics of photoexcited carriers in semiconductors during the first tens of femtosecond after laser excitation1–3. In particular, the ultrafast thermaliz...

    Mohamed A. Osman, Novat Nintunze in Hot Carriers in Semiconductors (1996)

  14. No Access

    Article

    Arylidene polymers

    A new class of polyconjugated polymers namely poly(2,5-arylidenecyclopentanone) and poly(2,6-arylidenecyclohexanone) has been obtained by condensation of cyclopentanone or cyclohexanone with terephthaldehyde. ...

    Mohamed A. Abd-Alla, Maher F. El-Zohry, Mohamed A. Osman in Polymer Bulletin (1991)