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  1. Article

    Open Access

    Targeted Literature Review of the Burden of Respiratory Syncytial Infection among High-Risk and Elderly Patients in Asia Pacific Region

    The burden of respiratory syncytial virus (RSV), which causes acute respiratory illness, is well recognized among the pediatric population but also imposes a significant risk to the elderly (age ≥ 60) and thos...

    Daisuke Kurai, JoonYoung Song, Yhu-Chering Huang in Infectious Diseases and Therapy (2023)

  2. Article

    Open Access

    Effectiveness of neutralizing antibody cocktail in hemodialysis patients: a case series of 20 patients treated with or without REGN-COV2

    The number of patients with SARS-CoV-2 infection continues to increase, and it has become a global pandemic. Although there is an urgent need to establish an effective treatment, the medication available for d...

    Shigehisa Arikawa, Kazuhito Fukuoka in Clinical and Experimental Nephrology (2022)

  3. Article

    Open Access

    Pilot study for risk assessment of aspiration pneumonia based on oral bacteria levels and serum biomarkers

    Aspiration pneumonia is a serious problem among elderly patients; it is caused by many risk factors including dysphagia, poor oral hygiene, malnutrition, and sedative medications. The aim of this study was to ...

    Tomotaka Nishizawa, Yuichi Niikura, Keiichi Akasaka in BMC Infectious Diseases (2019)

  4. Article

    Open Access

    Serum sST2 levels predict severe exacerbation of asthma

    Neutrophilic inflammation is associated with poorly controlled asthma. Serum levels of sST2, a soluble IL-33 receptor, increase in neutrophilic lung diseases. We hypothesized that high serum sST2 levels in sta...

    Masato Watanabe, Keitaro Nakamoto, Toshiya Inui, Mitsuru Sada in Respiratory Research (2018)

  5. No Access

    Article

    Diagnostic Value of Vascular Endothelial Growth Factor, Transforming Growth Factor-β, Interleukin-8, and the Ratio of Lactate Dehydrogenase to Adenosine Deaminase in Pleural Effusion

    We studied the diagnostic value of cytokines, including vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β), and interleukin-8 (IL-8), and the ratio of lactate dehydrogenase (LDH) t...

    Takeshi Saraya, Kosuke Ohkuma, Takayasu Watanabe, Sunao Mikura, Fumi Kobayashi in Lung (2018)

  6. Article

    Open Access

    Molecular evolution of haemagglutinin (H) gene in measles virus

    We studied the molecular evolution of the haemagglutinin (H) gene (full length) in all genotypes (24 genotypes, 297 strains) of measles virus (MeV). The gene’s evolutionary timescale was estimated by the Bayesian...

    Hirokazu Kimura, Mika Saitoh, Miho Kobayashi, Haruyuki Ishii in Scientific Reports (2015)

  7. No Access

    Article

    Mycoplasma pneumoniae Extract Induces an IL-17-Associated Inflammatory Reaction in Murine Lung: Implication for Mycoplasmal Pneumonia

    Mycoplasma pneumoniae (Mp) may cause immune cell reactions as pivotal aspects of this clinically common respiratory pathogen. Our aim is to determine if Mp extract induces a cellular immune respo...

    Daisuke Kurai, Kazuhide Nakagaki, Hiroo Wada, Takeshi Saraya in Inflammation (2013)

  8. No Access

    Article

    Nationwide surveillance of bacterial respiratory pathogens conducted by the Surveillance Committee of Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Clinical Microbiology in 2009: general view of the pathogens’ antibacterial susceptibility

    For the purpose of nationwide surveillance of antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, the Japanese Society of Chemotherapy (JSC) started a survey in 2006. From 2...

    Akira Watanabe, Katsunori Yanagihara in Journal of Infection and Chemotherapy (2012)

  9. No Access

    Article

    Nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2008: general view of the pathogens’ antibacterial susceptibility

    For the purpose of nationwide surveillance of the antimicrobial susceptibility of bacterial respiratory pathogens collected from patients in Japan, the Japanese Society of Chemotherapy conducted a third year o...

    Yoshihito Niki, Hideaki Hanaki, Tetsuya Matsumoto in Journal of Infection and Chemotherapy (2011)