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  1. No Access

    Article

    Snoring, obstructive sleep apnea, and upper respiratory tract infection in elementary school children in Japan

    Both obstructive sleep apnea (OSA) and the common cold are disorders of the upper respiratory tract, and may be associated. However, studies on the association between OSA and upper respiratory tract infection...

    Takayuki Kitazawa, Hiroo Wada, Keisuke Onuki, Ritsuko Furuya in Sleep and Breathing (2024)

  2. Article

    Open Access

    Working hours of full-time hospital physicians in Japan: a cross-sectional nationwide survey

    The culture of excessively long overtime work in Japan has not been recently addressed. New legislation on working hours, including a limitation on maximum overtime work for physicians, will be enforced in 202...

    Soichi Koike, Hiroo Wada, Sachiko Ohde, Hiroo Ide, Kenichiro Taneda in BMC Public Health (2024)

  3. No Access

    Article

    Impaired psychomotor vigilance associated with sleep-disordered breathing in women working in the care of older adults in Japan

    With a rapidly aging society, there is increasing interest in the health of female workers in the field of care services for older adults due to increasing demands to maintain 24-h care and to support older ad...

    Narihisa Miyachi, Ai Ikeda, Ronald Filomeno, Hiroo Wada in Sleep and Breathing (2022)

  4. Article

    Open Access

    Sleep Apnea Syndrome (SAS) Clinical Practice Guidelines 2020

    The prevalence of sleep-disordered breathing (SDB) is reportedly very high. Among SDBs, the incidence of obstructive sleep apnea (OSA) is higher than previously believed, with patients having moderate-to-sever...

    Tsuneto Akashiba, Yuichi Inoue, Naohisa Uchimura in Sleep and Biological Rhythms (2022)

  5. Article

    Open Access

    Long-term effect of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea

    Obstructive sleep apnea (OSA) is a common cause of hypertension. Previous studies have demonstrated beneficial short-term effects of continuous positive airway pressure (CPAP) therapy on blood pressure. Howeve...

    Ryutaro Shirahama, Takeshi Tanigawa, Yoshifumi Ida, Kento Fukuhisa in Scientific Reports (2021)

  6. No Access

    Article

    Association of sleep-disordered breathing and alcohol consumption with hypertension among Japanese male bus drivers

    There is limited evidence regarding the combined effects of sleep-disordered breathing (SDB) and alcohol consumption on hypertension. The aim of this study was to examine the combined effects of SDB and alcoho...

    Noriko Sakiyama, Kiyohide Tomooka, Koutatsu Maruyama in Hypertension Research (2021)

  7. Article

    Open Access

    Dual interleukin-17A/F deficiency protects against acute and chronic response to cigarette smoke exposure in mice

    IL-17A and IL-17F are both involved in the pathogenesis of neutrophilic inflammation observed in COPD and severe asthma. To explore this, mice deficient in both Il17a and Il17f and wild type (WT) mice were expose...

    Hiroo Wada, Masuo Nakamura, Shin-Ichi Inoue, Akihiko Kudo in Scientific Reports (2021)

  8. Article

    Open Access

    Low BMI and weight loss aggravate COPD mortality in men, findings from a large prospective cohort: the JACC study

    To clarify how low BMI and weight loss were associated with risk of chronic obstructive pulmonary disease (COPD) mortality, in a large prospective cohort of the general population across Japan, the Japan Colla...

    Hiroo Wada, Ai Ikeda, Koutatsu Maruyama, Kazumasa Yamagishi in Scientific Reports (2021)

  9. Article

    Open Access

    Sleep disordered breathing and subjective excessive daytime sleepiness in relation to the risk of motor vehicle crash: the Toon Health Study

    Sleep disordered breathing (SDB) is a significant cause of motor vehicle crash (MVC). We conducted a prospective cohort study among 1047 Japanese community-dwellers to detect whether the presence or absence of...

    Ryotaro Matsuo, Takeshi Tanigawa, Kiyohide Tomooka, Ai Ikeda in Scientific Reports (2020)

  10. Article

    Correction to: The Association Between Obesity and Hyperactivity/Anxiety Among Elementary School Students in Japan

    The original article has been corrected

    Yohei Suzuki, Ai Ikeda, Koutatsu Maruyama in International Journal of Behavioral Medici… (2020)

  11. No Access

    Article

    Association of employment and company size with lung cancer screening participation among Japanese based on the socioeconomic conditions using the Comprehensive Survey of Living Conditions

    The proportion of non-regularly employed persons has increased in Japan, but few studies have examined the relationship between employment status and lung cancer screening (LCS) participation.

    Mitsuya Maeda, Ronald Filomeno, Yumi Kawata in International Journal of Clinical Oncology (2020)

  12. No Access

    Article

    The association between obesity and hyperactivity/anxiety among elementary school students in Japan

    We aimed to evaluate the association between hyperactivity/anxiety and obesity among elementary school students in Matsuyama City, Japan.

    Yohei Suzuki, Ai Ikeda, Koutatsu Maruyama in International Journal of Behavioral Medici… (2020)

  13. No Access

    Article

    Association Between Employment Status and Short Sleep Duration Among Middle-Aged Japanese: the Survey on Time Use and Leisure Activities

    Short sleep duration (SSD) is reported to be highly associated with socio-economic status. There are few studies on the relationship between employment status and SSD in Japan.

    Mitsuya Maeda, Ronald Filomeno, Yumi Kawata in International Journal of Behavioral Medici… (2020)

  14. No Access

    Article

    The association of coffee consumption and oxygen desaturation index during sleep among Japanese male workers

    Coffee is a major caffeine-containing food source that can be used for treatment of apnea in prematurity. However, few studies have examined the association between coffee consumption and sleep-disordered brea...

    Asuka Takabayashi, Koutatsu Maruyama, Yasuhiko Tanno, Susumu Sakurai in Sleep and Breathing (2019)

  15. Article

    Open Access

    Recurrent sick leave and resignation rates among female cancer survivors after return to work: the Japan sickness absence and return to work (J-SAR) study

    To date, there have not been any workforce-based Japanese cohort studies investigating work sustainability after return to work (RTW). The objective of this study was to investigate the post-RTW cumulative rec...

    Motoki Endo, Yasuo Haruyama, Go Muto, Yuya Imai, Kiyomi Mitsui in BMC Public Health (2019)

  16. No Access

    Article

    Prevalence of sleep-disordered breathing among women working in the aged care services in Japan

    The aim of this study was to examine the prevalence of sleep-disordered breathing (SDB) in women working in the field of aged care in Japan.

    Yuka Suzuki, Ai Ikeda, Hiroo Wada in International Archives of Occupational and… (2019)

  17. Article

    Changes in bone metabolism after gastric cancer surgery in male patients: a prospective observational study

    Several retrospective studies have shown that bone disorders occur after gastric cancer surgery. This study was designed to prospectively evaluate the changes in bone metabolism after gastrectomy for gastric c...

    Yosuke Atsumi, Yasushi Rino, Hiroo Wada, Yuichi Kitani, Yukihiro Ozawa in Gastric Cancer (2019)

  18. No Access

    Article

    Systematic review and meta-analysis of histopathological predictive factors for lymph node metastasis in T1 colorectal cancer

    In this study we examined whether histopathological findings, specifically lymphatic vessel invasion identified by an anti-human podoplanin antibody, and several other factors are associated with lymph node me...

    Hiroo Wada, Manabu Shiozawa, Kayoko Katayama in Journal of Gastroenterology (2015)

  19. No Access

    Article

    Lymphatic invasion identified with D2-40 immunostaining as a risk factor of nodal metastasis in T1 colorectal cancer

    The management of T1 colorectal cancer after local resection is controversial. Regional lymph node metastasis often occurs, requiring subsequent colonic resection. The aim of this study was to reevaluate the r...

    Hiroo Wada, Manabu Shiozawa, Nobuhiro Sugano in International Journal of Clinical Oncology (2013)

  20. No Access

    Article

    Mycoplasma pneumoniae Extract Induces an IL-17-Associated Inflammatory Reaction in Murine Lung: Implication for Mycoplasmal Pneumonia

    Mycoplasma pneumoniae (Mp) may cause immune cell reactions as pivotal aspects of this clinically common respiratory pathogen. Our aim is to determine if Mp extract induces a cellular immune respo...

    Daisuke Kurai, Kazuhide Nakagaki, Hiroo Wada, Takeshi Saraya in Inflammation (2013)

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