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  1. No Access

    Article

    Selective, efficient modulation of activated CD4+ αβT cells by the novel humanized antibody GZ-αβTCR targeting human αβTCR

    Allograft rejection and immunosuppression are two major issues in transplantation medicine. The specific targeting of alloreactive T cells, the initiators and promoters of allograft rejection, would be a promi...

    G Blank, C Welker, J Haarer, M Sterk, S Nadalin, V A C Yañez… in Bone Marrow Transplantation (2015)

  2. No Access

    Article

    Generation, selection and preclinical characterization of an Fc-optimized FLT3 antibody for the treatment of myeloid leukemia

    The therapeutic efficacy of humanized or chimeric second-generation antitumor antibodies is clearly established, but often limited. In recent years, defined modifications of the glycosylation pattern or the am...

    M Hofmann, L Große-Hovest, T Nübling, E Pyż, M L Bamberg, S Aulwurm… in Leukemia (2012)

  3. No Access

    Article

    A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors

    Positively selected CD34+ hematopoietic stem cells from unrelated donors (UD-HSCT) have been successfully transplanted, but little is known about immune reconstitution in this setting. Here we report a prospectiv...

    M Eyrich, C Leiler, P Lang, K Schilbach, M Schumm, P Bader… in Bone Marrow Transplantation (2003)

  4. No Access

    Chapter and Conference Paper

    Immune Reconstitution after Haploidentical Stem Cell Transplantation

    With increasing efficacy and safety of the procedure in recent years, the transplantation of hematopoietic stem cells has become an important therapeutic modality for patients with a variety of malignant and n...

    P.G. Schlegel, C. Leiler, T. Croner, P. Lang… in Transplantation in Hematology and Oncology… (2003)