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Article
Formation of complexes of antimicrobial agent norfloxacin with antitumor antibiotics of anthracycline series
The formation of complexes in solutions of the norfloxacin antimicrobial agent (NOR) with daunomycin (DAU) and nogalamycin (NOG), antitumor anthracycline antibiotics, was studied using 1H NMR spectroscopy. Based ...
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Article
Self-association of daunomycin antibiotic in various buffer solutions
The self-association of an antitumor antibiotic, daunomycin (DAU), in various buffer solutions, including water-salt solutions, phosphate buffer, HEPES, and TRIS, was studied by 1D and 2D 1H NMR spectroscopy at 5...
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Article
Analysis by Means of 1H NMR Spectroscopy of Heteroassociaion in Water Solution of Antitumor Antibiotics Daunomycin and Actinomycin D
Heteroassociation of aromatic antitumor antibiotics daunomycin (DAU) and actinomycin D (AMD) was investigated using 1D and 2D 1H NMR spectroscopy (at 500 MHz) and molecular mechanics procedure with the goal of es...
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Article
Structural and thermodynamic analysis of heteroassociation of daunomycin and flavin mononucleotide molecules in water by 1H NMR spectroscopy
Heteroassociation of the antitumor antibiotic daunomycin (DAU) with flavin mononucleotide (FMN) has been investigated by one-and two-dimensional 1H NMR spectroscopy (500 MHz) in a water solution to determine the ...
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Article
1H NMR Study of Heteroassociation of Ethidium Homodimer and Propidium Iodide in Water
1D and 2D 1H NMR spectroscopy (500 MHz) was used to study heteroassociation of the bifunctional intercalator ethidium homodimer (EBH) with a phenanthridine dye propidium iodide (PI) in an aqueous salt (0.1 mol/l ...
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Article
Thermodynamic Analysis of Self-association of Actinocin Bis(2-dimethylaminoethyl)amide in Aqueous Solution by 1H NMR Spectroscopy
Self-association of a synthetic antibiotic, actinocin bis(2-dimethylaminoethyl)amide (ActII), in aqueous solution was studied by one- and two-dimensional 1H NMR spectroscopy (500 MHz).
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Article
1H NMR Study of Heteroassociation of Daunomycin and Propidium Iodide in Aqueous Solution
Heteroassociation of an anthracycline antibiotic Daunomycin (DAU) and phenanthridine dye Propidium iodide (PI) in aqueous solution was studied by 1H NMR spectroscopy. The complex PI-DAU is stabilized mainly by di...
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Article
Structural and Thermodynamic Analysis of Self-Association of Phenanthridine Dyes in Aqueous Solution by 1H NMR Spectroscopy
Self-association of phenanthridine dyes (ethidium monoazide EMB and ethidium diazide EDC) in aqueous solution was studied by one- and two-dimensional 1H NMR (500 MHz). 2D-TOCSY and 2D-ROESY experiments were used ...
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Article
1H NMR Analysis of Heteroassociation of Caffeine with Mitoxanthrone in Aqueous Solution
Heteroassociation of caffeine (CAF) with the antibiotic mitoxanthrone (novatrone, NOV) in aqueous solution was studied by one-dimensional (1D) and two-dimensional (2D) 1H NMR spectroscopy (500 MHz). The concentra...
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Article
Structural and Thermodynamic Analysis of Daunomycin Binding with Desoxyhexanucleotides with Different Base Sequences by NMR Spectroscopy
Complexation of the anthracycline antibiotic daunomycin (DAU) with self-complementary desoxyhexanucleotides with different base sequences in the chain, 5′-d(CGTACG) and 5′-d(CGCGCG), is studied in aqueous solutio...
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Article
1H nmr study of heteroassociation of caffeine with acridine orange in aqueous solution
The molecular mechanism of the action of caffeine (CAF) as a complexing interceptor of aromatic ligands intercalated in DNA is considered using a typical intercalant — acridine orange (AO) dye. Hetero-associat...
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Article
Complexation of the antibiotic daunomycin with desoxytetraribonucleoside triphosphate 5’-d(CpGpCpG) in aqueous solution
This paper presents the results of our study of the complexation of the antibiotic daunomycin with desoxytetranucleotide 5’-d(CpGpCpG) in aqueous salt solution by one- and two-dimensional (2D-TOCSY and 2D-NOESY)1
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Article
Analysis of the interaction of ethidium bromide with a DNA octamer 5’-d(GpApCpApTpGpTpC) in aqueous solution using1H NMR data
Complexation of a phenanthridine dye ethidium bromide with a desoxyoligonucleotide 5’-d(GpApCpAp-TpGpTpC) in aqueous salt solution is studied by one- and two-dimensional1H NMR spectroscopy. Two-dimensional correl...
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Article
Investigation of the interaction of proflavine with deoxytetraribonucleoside triphosphate 5′-d(CpGpCpG) in aqueous solution by one-dimensional and two-dimensional1H NMR spectroscopy
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Article
Thermodynamic analysis of the interaction between proflavine and the deoxytetraribonucleotide 5′-d(CpGpCpG) using proton magnetic resonance data