52 Result(s)
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Christopher B. Forrest
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Article
Clinical characteristics and favorable treatment responses of recurrent focal segmental glomerulosclerosis or steroid-resistant nephrotic syndrome in children after kidney transplantation
Recurrence of focal segmental glomerulosclerosis (FSGS) or steroid-resistant nephrotic syndrome (SRNS) after kidney transplant leads to significant morbidity and potentially earlier allograft loss. To date how...
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Article
Open AccessSpectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program
Multi-system inflammatory syndrome in children (MIS-C) is a severe post-acute sequela of SARS-CoV-2 infection in children, and there is a critical need to unfold its highly heterogeneous disease patterns. Our ...
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Article
Open AccessClinical course and management of children with IgA vasculitis with nephritis
IgA vasculitis is the most common vasculitis in children and is often complicated by acute nephritis (IgAVN). Risk of chronic kidney disease (CKD) among children with IgAVN remains unknown. This study aimed to...
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Article
Open AccessElectronic health records identify timely trends in childhood mental health conditions
Electronic health records (EHRs) data provide an opportunity to collect patient information rapidly, efficiently and at scale. National collaborative research networks, such as PEDSnet, aggregate EHRs data acr...
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Article
The real world experience of pediatric primary hyperoxaluria patients in the PEDSnet clinical research network
The rarity of primary hyperoxaluria (PH) challenges our understanding of the disease. The purpose of our study was to describe the course of clinical care in a United States cohort of PH pediatric patients, hi...
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Article
Open AccessBiologic Abatement and Capturing Kids’ Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA): study protocol for a randomized pragmatic trial
The effectiveness of biologic therapies, primarily tumor necrosis factor inhibitors (TNFi), for children with spondyloarthritis (SpA) has made inactive disease a realistic patient outcome. However, biologic th...
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Reference Work Entry In depth
Healthy Pathways Child Report Scales
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Reference Work Entry In depth
Healthy Pathways Parent Report Scales
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Article
Open AccessThe Gross Developmental Potential (GDP2): a new approach for measuring human potential and wellbeing
Many factors influence the health and well-being of children and the adults they will become. Yet there are significant gaps in how trajectories of healthy development are measured, how the potential for leadi...
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Article
Does Living near Trees and Other Vegetation Affect the Contemporaneous Odds of Asthma Exacerbation among Pediatric Asthma Patients?
Vegetation may influence asthma exacerbation through effects on aeroallergens, localized climates, air pollution, or children’s behaviors and stress levels. We investigated the association between residential ...
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Article
Antibiotics prior to age 2 years have limited association with preschool growth trajectory
Prior studies of early antibiotic use and growth have shown mixed results, primarily on cross-sectional outcomes. This study examined the effect of oral antibiotics before age 24 months on growth trajectory at...
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Article
Open AccessPreliminary development of recommendations for the inclusion of patient-reported outcome measures in clinical quality registries
Clinical quality registries (CQRs) monitor compliance against optimal practice and provide feedback to the clinical community and wider stakeholder groups. Despite a number of CQRs having incorporated the pati...
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Article
Open AccessAn efficient and accurate distributed learning algorithm for modeling multi-site zero-inflated count outcomes
Clinical research networks (CRNs), made up of multiple healthcare systems each with patient data from several care sites, are beneficial for studying rare outcomes and increasing generalizability of results. W...
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Article
Open AccessClinical data for paediatric research: the Swiss approach
Continuous improvement of health and healthcare system is hampered by inefficient processes of generating new evidence, particularly in the case of rare diseases and paediatrics. Currently, most evidence is ge...
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Article
Using nationally representative percentiles to interpret PROMIS pediatric measures
This study’s aim was to use a representative sample of the US pediatric population to estimate percentiles for several PROMIS pediatric measures: Anger, Anxiety, Depressive Symptoms, Family Relationships, Fati...
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Article
Are there birth cohort effects in disparities in child obesity by maternal education?
Children belonging to the same birth cohort (i.e., born in the same year) experience shared exposure to a common obesity-related milieu during the critical early years of development—e.g., secular beliefs and ...
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Article
Better sleep, better life? How sleep quality influences children’s life satisfaction
To assess the association between children’s sleep quality and life satisfaction; and to evaluate the underlying mechanisms of this relationship.
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Article
Investigating child self-report capacity: a systematic review and utility analysis
To identify and evaluate methods for assessing pediatric patient-reported outcome (PRO) data quality at the individual level.
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Article
Privacy-protecting multivariable-adjusted distributed regression analysis for multi-center pediatric study
Privacy-protecting analytic approaches without centralized pooling of individual-level data, such as distributed regression, are particularly important for vulnerable populations, such as children, but these m...
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Article
Open AccessEstablishing the content validity of PROMIS Pediatric pain interference, fatigue, sleep disturbance, and sleep-related impairment measures in children with chronic kidney disease and Crohn’s disease
PROMIS Pediatric patient-reported outcome measures were developed with children from the general population, and their content validity has not been established in children with chronic disease. This study was...
