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Article
Open AccessNo increase in inflammation in late-life major depression screened to exclude physical illness
Depression is a common and debilitating disorder in the elderly. Late-life depression (LLD) has been associated with inflammation and elevated levels of proinflammatory cytokines including interleukin (IL)-1β,...
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Article
Genetic Predictors of the Clinical Response to Opioid Analgesics
This review uses a candidate gene approach to identify possible pharmacogenetic modulators of opioid therapy, and discusses these modulators together with demonstrated genetic causes for the variability in cli...
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Article
Drug Interactions with Patient-Controlled Analgesia
Patient-controlled analgesia (PCA) has become standard procedure in the clinical treatment of pain. Its widespread use in patients with all kinds of diseases opens a variety of possible interactions between an...