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  1. No Access

    Article

    Genetic Predictors of the Clinical Response to Opioid Analgesics

    This review uses a candidate gene approach to identify possible pharmacogenetic modulators of opioid therapy, and discusses these modulators together with demonstrated genetic causes for the variability in cli...

    Dr Jörn Lötsch, Carsten Skarke, Jürgen Liefhold… in Clinical Pharmacokinetics (2004)

  2. No Access

    Article

    Morphine-6-Glucuronide

    Morphine-6-β-glucuronide (M6G) is an opioid agonist that plays a role in the clinical effects of morphine. Although M6G probably crosses the blood-brain barrier with difficulty, during long term morphine admin...

    Dr Jörn Lötsch, Gerd Geisslinger in Clinical Pharmacokinetics (2001)