Search
Search Results
-
Dynamicity of brain network organization & their community architecture as characterizing features for classification of common mental disorders from whole-brain connectome
The urgency of addressing common mental disorders (bipolar disorder, attention-deficit hyperactivity disorder (ADHD), and schizophrenia) arises from...
-
Interactions between metabotropic glutamate and CB1 receptors: implications for mood, cognition, and synaptic signaling based on data from mGluR and CB1R-targeting drugs
Metabotropic glutamate receptors (mGluRs) are part of the G protein-coupled receptors (GPCRs) family. They are coupled to G αq (group I) or G i/o ...
-
Considerations for Planning Effective and Appealing Advisory Boards and Other Small-Group Meetings with Health Care Providers: Importance of Participant Preferences
BackgroundTo optimize cost effectiveness, engagement, reach, inclusivity, insight quality and quantity, and participant satisfaction of...
-
GluK1 kainate receptors are necessary for functional maturation of parvalbumin interneurons regulating amygdala circuit function
Parvalbumin expressing interneurons (PV INs) are key players in the local inhibitory circuits and their developmental maturation coincides with the...
-
Paracetamol Combination Therapy for Back Pain and Osteoarthritis: A Systematic Review and Meta-Analyses
Background and ObjectiveAlthough paracetamol (acetaminophen) combined with other analgesics can reduce pain intensity in some pain conditions, its...
-
-
Short-Term Neurologic Complications in Patients Undergoing Extracorporeal Membrane Oxygenation Support: A Review on Pathophysiology, Incidence, Risk Factors, and Outcomes
Regardless of the type, extracorporeal membrane oxygenation (ECMO) requires the use of large intravascular cannulas and results in multiple...
-
Applications of functional neurotransmitter release imaging with genetically encoded sensors in psychiatric research
Psychiatric research encompasses diverse methodologies to understand the complex interplay between neurochemistry and behavior in mental health...
-
Alzheimer’s Disease: Combination Therapies and Clinical Trials for Combination Therapy Development
Alzheimer’s disease (AD) is a complex multifaceted disease. Recently approved anti-amyloid monoclonal antibodies slow disease progression by...
-
Why do adolescents attempt suicide? Insights from leading ideation-to-action suicide theories: a systematic review
Suicide is a leading cause of death among adolescents, and recent suicide theories have sought to clarify the factors that facilitate the transition...
-
Efficacy and Safety of BP02 (Trastuzumab Biosimilar) in HER2-Positive Metastatic Breast Cancer: A Multicenter Phase III Study
Background and ObjectiveTrastuzumab targets human epidermal growth factor receptor 2 (HER2) receptors and is indicated for treating HER2-positive...
-
-
Development of a Predictive Model for Potentially Inappropriate Medications in Older Patients with Cardiovascular Disease
BackgroundOlder patients with cardiovascular disease (CVD) are highly susceptible to adverse drug reactions due to age-related physiological changes...
-
Outcomes of Rituximab-abbs versus Rituximab in Patients with Diffuse Large B-Cell Lymphoma in a Noninferiority Study
BackgroundRituximab with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) is one of the first line treatments for diffuse large...
-
Adis summary of research: Safety, tolerability and pharmacokinetics of aripiprazole 2-monthly formulation in patients with schizophrenia or bipolar I disorder
The once-monthly long-acting injectable (LAI) formulation of aripiprazole, an atypical antipsychotic that stabilizes the dopamine-serotonin system,...
-
cGMP compliant one-step, one-pot automated [18F]FBnTP production for clinical imaging of mitochondrial activity
Background4-[ 18 F]fluorobenzyl-triphenylphosphonium ([ 18 F]FBnTP) is a lipophilic cation PET tracer. The cellular uptake of [ 18 F]FBnTP is correlated...
-
Commercial Versus Compounded Preparations in Pediatric Ophthalmology
Many conditions managed by pediatric ophthalmologists are rare diseases, and even if pharmacological treatments are available, these have often not...
-
Real-World Safety and Effectiveness of Letermovir in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation: Final Results of Post-Marketing Surveillance in Japan
Background and ObjectiveCytomegalovirus (CMV) is a common opportunistic infection after allogenic hematopoietic stem cell transplantation...
