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Article
Freezing life within refractory, amorphous silicon dioxide
The cryopreservation of biological samples is hindered by ice formation and the need to maintain samples under cryogenic conditions during storage and transportation. Silicification offers a simple method for ...
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Article
Open AccessCTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells
Impaired autophagy, a cellular digestion process that eliminates proteins and damaged organelles, has been implicated in neurodegenerative diseases, including motor neuron disorders. Motor neuron targeted upre...
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Article
Open AccessLong-term whole blood DNA preservation by cost-efficient cryosilicification
Deoxyribonucleic acid (DNA) is the blueprint of life, and cost-effective methods for its long-term storage could have many potential benefits to society. Here we present the method of in situ cryosilicificatio...
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Article
The impact of metal do** on fumed silica structure and amino acid thermal condensation catalytic properties
Fumed silica nanoparticles (FSN) are one of the most common synthetic forms of silica, but prolonged exposure leads to cell toxicity and apoptosis due to reactive oxygen species (ROS) generation and cell membr...
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Chapter
Emerging Lipid-Coated Silica Nanoparticles for Cancer Therapy
Siliceous nanomaterials are attractive candidates for applications in cancer theranostics due to their precise synthesis control, ease of surface functionalization, accuracy of characterization, controllable r...
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Article
Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications
Natural silica and silicates are predominantly crystalline and constitute the most abundant components of the Earth’s crust. Man-made silica is typically amorphous and manufactured in tonnage quantities for co...
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Article
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine
An amendment to this paper has been published and can be accessed via a link at the top of the paper
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Article
On the issue of transparency and reproducibility in nanomedicine
Following our call to join in the discussion over the suitability of implementing a reporting checklist for bio–nano papers, the community responds.
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Article
Open AccessMathematical modeling in cancer nanomedicine: a review
Cancer continues to be among the leading healthcare problems worldwide, and efforts continue not just to find better drugs, but also better drug delivery methods. The need for delivering cytotoxic agents selec...
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Article
Engineering of large-pore lipid-coated mesoporous silica nanoparticles for dual cargo delivery to cancer cells
Lipid-coated mesoporous silica nanoparticles (LC-MSNs) have recently emerged as a next-generation cargo delivery nanosystem combining the unique attributes of both the organic and inorganic components. The hig...
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Article
Open AccessEstablishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
The progress of nanoparticle (NP)-based drug delivery has been hindered by an inability to establish structure-activity relationships in vivo. Here, using stable, monosized, radiolabeled, mesoporous silica nan...
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Article
Open AccessAuthor Correction: Ultra-thin enzymatic liquid membrane for CO2 separation and capture
The original version of this Article contained an error in the spelling of the author Stanley S. Chou, which was incorrectly given as Stan Chou. This has now been corrected in both the PDF and HTML versions of...
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Article
Open AccessUnderstanding the Connection between Nanoparticle Uptake and Cancer Treatment Efficacy using Mathematical Modeling
Nanoparticles have shown great promise in improving cancer treatment efficacy while reducing toxicity and treatment side effects. Predicting the treatment outcome for nanoparticle systems by measuring nanopart...
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Article
Open AccessUltra-thin enzymatic liquid membrane for CO2 separation and capture
The limited flux and selectivities of current carbon dioxide membranes and the high costs associated with conventional absorption-based CO2 sequestration call for alternative CO2 separation approaches. Here we de...
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Article
Open AccessBio-inspired Murray materials for mass transfer and activity
Both plants and animals possess analogous tissues containing hierarchical networks of pores, with pore size ratios that have evolved to maximize mass transport and rates of reactions. The underlying physical p...
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Article
Open AccessUnderstanding catalysis in a multiphasic two-dimensional transition metal dichalcogenide
Establishing processing–structure–property relationships for monolayer materials is crucial for a range of applications spanning optics, catalysis, electronics and energy. Presently, for molybdenum disulfide, ...
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Article
Open AccessSilica bioreplication preserves three-dimensional spheroid structures of human pluripotent stem cells and HepG2 cells
Three-dimensional (3D) cell cultures produce more in vivo-like multicellular structures such as spheroids that cannot be obtained in two-dimensional (2D) cell cultures. Thus, they are increasingly employed as mod...
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Article
Open AccessSynthetic fossilization of soft biological tissues and their shape-preserving transformation into silica or electron-conductive replicas
Structural preservation of complex biological systems from the subcellular to whole organism level in robust forms, enabling dissection and imaging while preserving 3D context, represents an enduring grand cha...
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Chapter
Dip Coating
In this chapter a wide a range of examples—from the putative simple dip coating process, where a substrate is withdrawn from the coating solution at a constant rate, to the more advanced evaporation induced se...
