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Article
Open AccessLipid-coated mesoporous silica nanoparticles for anti-viral applications via delivery of CRISPR-Cas9 ribonucleoproteins
Emerging and re-emerging viral pathogens present a unique challenge for anti-viral therapeutic development. Anti-viral approaches with high flexibility and rapid production times are essential for combating th...
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Article
Open AccessOrthogonal luminescence lifetime encoding by intermetallic energy transfer in heterometallic rare-earth MOFs
Lifetime-encoded materials are particularly attractive as optical tags, however examples are rare and hindered in practical application by complex interrogation methods. Here, we demonstrate a design strategy ...
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Article
Open AccessSingleplex, multiplex and pooled sample real-time RT-PCR assays for detection of SARS-CoV-2 in an occupational medicine setting
For workplaces which cannot operate as telework or remotely, there is a critical need for routine occupational SARS-CoV-2 diagnostic testing. Although diagnostic tests including the CDC 2019-Novel Coronavirus ...
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Article
Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications
Natural silica and silicates are predominantly crystalline and constitute the most abundant components of the Earth’s crust. Man-made silica is typically amorphous and manufactured in tonnage quantities for co...
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Article
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine
An amendment to this paper has been published and can be accessed via a link at the top of the paper
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Article
On the issue of transparency and reproducibility in nanomedicine
Following our call to join in the discussion over the suitability of implementing a reporting checklist for bio–nano papers, the community responds.
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Article
Open AccessEstablishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
The progress of nanoparticle (NP)-based drug delivery has been hindered by an inability to establish structure-activity relationships in vivo. Here, using stable, monosized, radiolabeled, mesoporous silica nan...
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Article
Open AccessDetection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors
Breast cancer detection using mammography has improved clinical outcomes for many women, because mammography can detect very small (5 mm) tumors early in the course of the disease. However, mammography fails t...
