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    Article

    Synthesis of 2′-Deoxy-2′-[18F]Fluoro-9-β-D-Arabinofuranosylguanine: a Novel Agent for Imaging T-Cell Activation with PET

    9-(β-D-Arabinofuranosyl)guanine (AraG) is a guanosine analog that has a proven efficacy in the treatment of T-cell lymphoblastic disease. To test the possibility of using a radiofluorinated AraG as an imaging age...

    Mohammad Namavari, Ya-Fang Chang, Brenda Kusler in Molecular Imaging and Biology (2011)

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    Article

    Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

    Expression of the human telomerase catalytic component, hTERT, in normal human somatic cells can reconstitute telomerase activity and extend their replicative lifespan1,2. We report here that at twice the normal ...

    Xu-Rong Jiang, Gretchen Jimenez, Edwin Chang, Maria Frolkis in Nature Genetics (1999)