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  1. No Access

    Article

    Synthesis and Characterization of 9-(4-[18F]Fluoro-3-(hydroxymethyl)butyl)-2-(phenylthio)-6-oxopurine as a Novel PET Agent for Mutant Herpes Simplex Virus Type 1 Thymidine Kinase Reporter Gene Imaging

    [18F]FHBG has been used as a positron emission tomography (PET) imaging tracer for the monitoring of herpes simplex virus type 1 thymidine kinase (HSV1-tk), a reporter gene for cell and gene therapy in humans. Ho...

    Takeshi Fuchigami, Tom Haywood, Gayatri Gowrishankar… in Molecular Imaging and Biology (2020)

  2. No Access

    Article

    Synthesis of [18F]-labelled Maltose Derivatives as PET Tracers for Imaging Bacterial Infection

    To develop novel positron emission tomography (PET) agents for visualization and therapy monitoring of bacterial infections.

    Mohammad Namavari, Gayatri Gowrishankar, Aileen Hoehne… in Molecular Imaging and Biology (2015)

  3. No Access

    Article

    A novel 18F-labeled two-helix scaffold protein for PET imaging of HER2-positive tumor

    Two-helix scaffold proteins (~ 5 kDa) against human epidermal growth factor receptor type 2 (HER2) have been discovered in our previous work. In this research we aimed to develop an 18F-labeled two-helix scaffold...

    Zheng Miao, Gang Ren, Lei Jiang… in European Journal of Nuclear Medicine and M… (2011)

  4. No Access

    Article

    Synthesis of 2′-Deoxy-2′-[18F]Fluoro-9-β-D-Arabinofuranosylguanine: a Novel Agent for Imaging T-Cell Activation with PET

    9-(β-D-Arabinofuranosyl)guanine (AraG) is a guanosine analog that has a proven efficacy in the treatment of T-cell lymphoblastic disease. To test the possibility of using a radiofluorinated AraG as an imaging age...

    Mohammad Namavari, Ya-Fang Chang, Brenda Kusler… in Molecular Imaging and Biology (2011)

  5. No Access

    Article

    64Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors

    The development of molecular probes based on novel engineered protein constructs is under active investigation due to the great potential of this generalizable strategy for imaging a variety of tumor targets.

    Zhen Cheng, Omayra Padilla De Jesus, Daniel J. Kramer… in Molecular Imaging and Biology (2010)

  6. No Access

    Article

    Direct Site-Specific Radiolabeling of an Affibody Protein with 4-[18F]Fluorobenzaldehyde via Oxime Chemistry

    In this study, we introduce a methodology for preparing 18F-labeled Affibody protein, specifically 18F-Anti-HER2 dimeric Affibody (14 kDa), for in vivo imaging of HER2neu with positron emission tomography (PET).

    Mohammad Namavari, Omayra Padilla De Jesus, Zhen Cheng… in Molecular Imaging and Biology (2008)

  7. No Access

    Article

    Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography

    Molecular imaging of a suicide transgene's expression will aid the development of efficient and precise targeting strategies, and imaging for cancer cell viability may assess therapeutic efficacy. We used the ...

    Shahriar S Yaghoubi, Jorge R Barrio, Mohammad Namavari… in Cancer Gene Therapy (2005)

  8. No Access

    Article

    Quantification of target gene expression by imaging reporter gene expression in living animals

    Ya**g Yu, Alexander J. Annala, Jorge R. Barrio, Tatsushi Toyokuni… in Nature Medicine (2000)