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33 Result(s)

within **n-Wei **e MD Remove this filter Obstetrics/Perinatology/Midwifery Remove this filter

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  1. No Access

    Article

    Effect of a Small Physiological Electric Field on Angiogenic Activity in First-Trimester Extravillous Trophoblast Cells

    Electrical stimulation induces significant angiogenesis in vivo. We have shown that electrical stimulation of trophoblast cells has important functions in aspects of angiogenesis. In this study, we investigate...

    Liyan Ye MD, Linbo Guan MS, ** Fan MD, Yinghui Liu MD… in Reproductive Sciences (2019)

  2. No Access

    Article

    Perioperative Intervention by β-Blockade and NF-κB Suppression Reduces the Recurrence Risk of Endometriosis in Mice Due to Incomplete Excision

    Despite the demonstrated efficacy of surgical treatment of endometriosis, recurrence after surgery still remains a formidable challenge. Surgery, especially when performed repeatedly, decreases ovarian reserve...

    Qiqi Long MD, PhD, Hanxi Zheng MD, **shi Liu MD, PhD… in Reproductive Sciences (2019)

  3. No Access

    Article

    Novel Mutations in CFAP44 and CFAP43 Cause Multiple Morphological Abnormalities of the Sperm Flagella (MMAF)

    Multiple morphological abnormalities of the sperm flagella (MMAF) is a rare disease that causes primary infertility. However, the genetic causes for approximately half of MMAF cases are unknown. Whole exome se...

    Yan-Wei Sha MM, **ong Wang PhD, **aohui Xu PhD, Zhi-Ying Su MD… in Reproductive Sciences (2019)

  4. No Access

    Article

    Genome-Wide Profiling of Long Noncoding RNA Expression Patterns in Women With Repeated Implantation Failure by RNA Sequencing

    To compare long noncoding RNA (lncRNA) and messenger RNA (mRNA) expression levels in endometrium between patients with repeated implantation failure (RIF) following in vitro fertilization (IVF)-embryo transfer...

    Min-Yan Chen MD, Guang-Dong Liao MD, Bin Zhou PhD, Le-Ni Kang PhD… in Reproductive Sciences (2019)

  5. No Access

    Article

    Further Evidence for Hypercoagulability in Women With Ovarian Endometriomas

    Our previous studies have shown that platelets play a crucial role in the development of endometriosis, and women with endometriosis appear to be in a state of hypercoagulability. However, a recent study could...

    Ding Ding MD, PhD, **shi Liu MD, PhD, Sun-Wei Guo PhD in Reproductive Sciences (2018)

  6. No Access

    Article

    Caloric Restriction Dramatically Stalls Lesion Growth in Mice With Induced Endometriosis

    Caloric restriction (CR) has been demonstrated to have many health-beneficial effects in many species, but whether CR can impede the development of endometriosis is unknown. To test the hypothesis that CR can ...

    Bo Yin MD, **shi Liu MD, PhD, Sun-Wei Guo PhD in Reproductive Sciences (2018)

  7. No Access

    Article

    Prenatal Growth Patterns and Birthweight Are Associated With Differential DNA Methylation and Gene Expression of Cardiometabolic Risk Genes in Human Placentas: A Discovery-Based Approach

    Inherent genetic programming and environmental factors affect fetal growth in utero. Epidemiologic data in growth-altered fetuses, either intrauterine growth restricted (IUGR) or large for gestational age (LGA...

    Pao-Yang Chen PhD, Alison Chu MD, Wen-Wei Liao MS… in Reproductive Sciences (2018)

  8. No Access

    Article

    Transvaginal Elastosonography as an Imaging Technique for Diagnosing Adenomyosis

    To test the hypothesis that the lesional stiffness as measured by transvaginal elastosonography (TVESG) correlates with the extent of fibrosis in adenomyotic (AM) lesions, and thus TVESG can be used to diagnos...

    **shi Liu MD, PhD, Ding Ding MD, PhD, Yunyun Ren MD, PhD… in Reproductive Sciences (2018)

  9. No Access

    Article

    MiR-203 Participates in Human Placental Angiogenesis by Inhibiting VEGFA and VEGFR2 Expression

    Angiogenesis during placentation is of great significance in maintaining normal pregnancy. However, the molecular mechanisms of this process are not clear. It has been reported that miR-203 plays a critical ro...

    Fulin Liu MM, Wanrong Wu MM, Kejia Wu MD, Yurou Chen MM… in Reproductive Sciences (2018)

  10. No Access

    Article

    Histological and Immunohistochemical Characterization of the Similarity and Difference Between Ovarian Endometriomas and Deep Infiltrating Endometriosis

    Ovarian endometrioma (OMA) and deep infiltrating endometriosis (DIE) have long been recognized to have different histology and, as such, postulated to be 2 separate disease entities. Few studies, however, have...

    **shi Liu MD, PhD, Qi Zhang MD, PhD, Sun-Wei Guo PhD in Reproductive Sciences (2018)

  11. No Access

    Article

    Reduced Expression of Eukaryotic Translation Initiation Factor 3 Subunit e and Its Possible Involvement in the Epithelial-Mesenchymal Transition in Endometriosis

    Epithelial-mesenchymal transition (EMT) is now well documented to be involved in the development of endometriosis through the promotion of invasion and fibrogenesis. To date, several factors have been reported...

    **anjun Cai MD, Minhong Shen MD, PhD, **shi Liu MD, PhD… in Reproductive Sciences (2018)

  12. No Access

    Article

    Endometriosis-Derived Thromboxane A2 Induces Neurite Outgrowth

    Hyperinnervation in endometriosis is now well documented, but so far only a few neurotrophins have been identified. Since endometriotic stromal cells secrete thromboxane A2 (TXA2), we sought to determine whether ...

    Dingmin Yan MD, **shi Liu MD, PhD, Sun-Wei Guo PhD in Reproductive Sciences (2017)

  13. No Access

    Article

    Origins and Progression of Adolescent Endometriosis

    Accumulating evidence indicates that adolescent endometriosis is common and often severe. Here we explore the possibility that seeding of naive endometrial progenitor cells into the pelvic cavity early in life...

    Ivo Brosens MD, PhD, Caroline E. Gargett PhD… in Reproductive Sciences (2016)

  14. No Access

    Article

    Cellular Changes Consistent With Epithelial–Mesenchymal Transition and Fibroblast-to-Myofibroblast Transdifferentiation in the Progression of Experimental Endometriosis in Baboons

    We have recently shown that platelets play important roles in development of endometriosis and proposed that endometriotic lesions are essentially wounds that undergo repeated tissue injury and repair (ReTIAR)...

    Qi Zhang MSc, Jie Duan MD, Mark Olson BS, Asgerally Fazleabas PhD… in Reproductive Sciences (2016)

  15. No Access

    Article

    Surgical History and the Risk of Endometriosis:A Hospital-Based Case-Control Study

    Women tend to receive more surgical procedures than men. Our mouse study shows that surgical stress promotes the development of endometriosis. This study was undertaken to test the hypothesis that surgery incr...

    **shi Liu MD, PhD, Qiqi Long MD, Sun-Wei Guo PhD in Reproductive Sciences (2016)

  16. No Access

    Article

    Endometriosis-Derived Stromal Cells Secrete Thrombin and Thromboxane A2, Inducing Platelet Activation

    Platelets have been recently revealed to play important roles in the development of endometriosis. However, it is unclear whether endometriotic lesions can secrete any platelet inducers outside the menstruatio...

    Sun-Wei Guo PhD, Yanbo Du MD, **shi Liu MD, PhD in Reproductive Sciences (2016)

  17. No Access

    Article

    Resveratrol Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice With Induced Adenomyosis

    In this study, we sought to determine whether resveratrol (RSV), a nonhormonal compound, would suppress the myometrial infiltration, improve pain behavior, lower stress level, improve the expression of some pr...

    Bo Zhu MD, Yumei Chen MD, Hong** Zhang MD, **shi Liu MD, PhD… in Reproductive Sciences (2015)

  18. No Access

    Article

    Evidence for a Hypercoagulable State in Women With Ovarian Endometriomas

    Endometriosis is a hormonal disease and also an inflammatory condition. Converging evidence indicates that inflammation and coagulation are 2 major host-defense systems that interact with each other. This stud...

    Qinjiao Wu MD, MSc, Ding Ding MD, PhD, **shi Liu MD, PhD… in Reproductive Sciences (2015)

  19. No Access

    Article

    The Role of Laminin α4 in Human Umbilical Vein Endothelial Cells and Pathological Mechanism of Preeclampsia

    Preeclampsia (PE) is associated with defective placental angiogenesis and poor placentation. Laminins are the main noncollagenous glycoproteins in basement membranes, and laminin α4 (LAMA4) promotes the migrat...

    Nan Shan MD, Xuemei Zhang MD, **aoqiu **ao PhD, Hua Zhang MD… in Reproductive Sciences (2015)

  20. No Access

    Article

    Dating Endometriotic Ovarian Cysts Based on the Content of Cyst Fluid and its Potential Clinical Implications

    This study was undertaken to test the hypotheses that, due to gradual accumulation of dead erythrocytes and their ingested products resulting from repeated hemorrhage, older endometriomas (whitish in color) co...

    Sun-Wei Guo PhD, Ding Ding MD, PhD, Minhong Shen MD… in Reproductive Sciences (2015)

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