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  1. No Access

    Article

    SRC-3 Plays a Critical Role in Human Umbilical Vein Endothelial Cells by Regulating the PI3K/Akt/mTOR Pathway in Preeclampsia

    Preeclampsia (PE) is currently thought to be characterized by oxidative stress which may lead to endothelial dysfunction. The normal function of vascular endothelium is essential to vascular homeostasis. Previ...

    Yu Yuan MD, Nan Shan MD, Bin Tan MD, Qinyin Deng MD… in Reproductive Sciences (2018)

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    Article

    The Role of Laminin α4 in Human Umbilical Vein Endothelial Cells and Pathological Mechanism of Preeclampsia

    Preeclampsia (PE) is associated with defective placental angiogenesis and poor placentation. Laminins are the main noncollagenous glycoproteins in basement membranes, and laminin α4 (LAMA4) promotes the migrat...

    Nan Shan MD, Xuemei Zhang MD, **aoqiu **ao PhD, Hua Zhang MD… in Reproductive Sciences (2015)

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    Article

    Downregulated Krüppel-Like Factor 8 Is Involved in Decreased Trophoblast Invasion Under Hypoxia–Reoxygenation Conditions

    Krüppel-like factor 8 (KLF8) is a pivotal transcription factor expressed in the human placenta that can regulate cell invasion. The objective of this study was to assess whether a hypoxia–reoxygenation (H/R) e...

    Zhongmei Yang MD, Bing Bai MD, **n Luo MD, **aoqiu **ao PhD… in Reproductive Sciences (2014)