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  1. No Access

    Article

    SRC-3 Plays a Critical Role in Human Umbilical Vein Endothelial Cells by Regulating the PI3K/Akt/mTOR Pathway in Preeclampsia

    Preeclampsia (PE) is currently thought to be characterized by oxidative stress which may lead to endothelial dysfunction. The normal function of vascular endothelium is essential to vascular homeostasis. Previ...

    Yu Yuan MD, Nan Shan MD, Bin Tan MD, Qinyin Deng MD… in Reproductive Sciences (2018)

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    Article

    The Role of MGAT5 in Human Umbilical Vein Endothelial Cells: Possible Relevance to the Pathological Mechanism of Preeclampsia

    Preeclampsia (PE) is associated with shallow invasion of the trophoblast and insufficient remodeling of the uterine spiral artery. Glycosylation reactions are catalyzed by glycosyltransferases including N-acet...

    Qinyin Deng MD, Ying Chen MD, Nanlin Yin MD, Nan Shan MD… in Reproductive Sciences (2017)

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    Article

    The Role of Laminin α4 in Human Umbilical Vein Endothelial Cells and Pathological Mechanism of Preeclampsia

    Preeclampsia (PE) is associated with defective placental angiogenesis and poor placentation. Laminins are the main noncollagenous glycoproteins in basement membranes, and laminin α4 (LAMA4) promotes the migrat...

    Nan Shan MD, Xuemei Zhang MD, **aoqiu **ao PhD, Hua Zhang MD… in Reproductive Sciences (2015)